Results 61 to 70 of about 16,431,127 (248)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Atención focalizada, desde la política social, a los adultos mayores institucionalizados del municipio Placetas, Cuba. / Focused attention, from the social policy, to the institutionalized older adults of the municipality Placetas, Cuba.

Novedades en Población, 2020
The high rate of population aging that Cuba has presented has led to the adoption of a policy for attention to the demographic dynamic, based on the guidelines of the economic and social policy of the Party and the Revolution.
Lucrines Azcuy Aguilera, Ariagnis Carrellón Pérez, Yamila Roque Doval   +2 more
doaj  

Social service review; a monthly summary of social service activities.

, 1915
Editors: Apr. 1915-Feb. 1916, G.E. Smith.--Mar 1916- M.L. Williamson.Mode of access: Internet.Organ of the Bureau of Social Service Information from Mar.
Bureau of Social Service Information, New York.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

“Focus on the young ones”: Discourses on substance abuse and age

Nordic Studies on Alcohol and Drugs, 2015
BACKGROUND & AIMS – Previous research has shown that age categories play a vital part in the decision-making processes of counsellors in substance abuse services, yet very little is known about how the meanings of “age” and “substance abuse” are ...
Selseng Lillian Bruland
doaj   +1 more source

THE SERVICE AND EDUCATIONAL MISSION OF THE CHURCH IN MODERN SOCIETY AS A FACTOR OF FORMING THE FUNDAMENTALS OF THE SOCIAL IDEAL

Освітній дискурс, 2020
The Church, having a rich experience of work in the social environment, tries not only to serve humanity, realizing its vocation, but also to fulfill the educational mission, which is unique in meaning, content and forms of expression.
Anatoliy Kysliy
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

MODELS OF GOOD PRACTICE REGARDING SOCIAL SERVICES FOR THE ELDERLY IN ROMANIA - QUALITATIVE APPROACH [PDF]

Revista Universitară de Sociologie, 2021
The elderly in Romania benefit from a set of social benefits and a wide range of social services depending on the needs identified by specialists. The main social services for seniors are residential centers, home care services and day centers.
Gianina CHIRUGU, Felicia ANDRIONI
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

To Be Supported, or Not to Be: Images of Older People in Policy and the Reality in Local Communities in Japan

Frontiers in Sociology, 2019
Social innovation is not only about tangible new products, services, policies, and laws, but also about changes in societal perceptions, values, and norms.
Ken Aoo, Noriko Abe, Mitsunobu R. Kano
doaj   +1 more source