Results 61 to 70 of about 2,756,058 (293)

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Environmental risks associated with quarry activities and its anthropogenic changes in Weija Hills, Ga South Municipal, Ghana

Discover Geoscience
Quarrying has become an important socio-economic activity in many societies as it provides several services for human well-being. Weija Hills at the Ga South Municipality in Ghana has been witnessing quarrying activities at various sections of the hills ...
Esther Bonful, Simon Kyei, Isaac Boateng
doaj   +1 more source

21st century social work: reducing re-offending - key practice skills [PDF]

, 2005
This literature review was commissioned by the Scottish Executive’s Social Work Services Inspectorate in order to support the work of the 21st Century Social Work Review Group.
Batchelor, S., Burnett, R., Knox, J., McNeill, F.   +3 more
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Adverse Childhood Experiences: The Protective and Therapeutic Potential of Nature

Frontiers in Psychology, 2020
Adverse childhood experiences (ACEs) are prevalent in many western populations. Large studies have put the likelihood of having at least one ACE above 50% of the general population.
Anna K. Touloumakos, Anna K. Touloumakos, Anna K. Touloumakos, Alexia Barrable   +3 more
doaj   +1 more source

Technology for social work education [PDF]

, 1996
The intention of this paper is to examine aspects of the role of information technology in social work education in relation to existing developments within an international context, conceptual issues concerning the application of CAL to the teaching of ...
Colombi, David, Hopkins, Tom
core   +3 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

The use of BDA strategy in extensive reading improves students' learning achievement

Research and Development in Education
Although there is empirical support for the Before-During-After (BDA) strategy, there is still a gap in its application in extensive reading programs, particularly in the context of English as a Foreign Language (EFL).
Elfrida BR. Silalahi, Bertha Resivia Gayatri, Emmanuel Kyei   +2 more
doaj   +1 more source

Skill Uncertainty and Social Inference [PDF]

SSRN Electronic Journal, 2007
Abstract Research in psychology indicates that individuals often make inferences regarding unknown individual qualities based on potentially irrelevant (but socially observable) information. This paper explores occupational choices when individuals receive imprecise signals regarding ability and use the observable characteristics of previously ...
openaire   +3 more sources