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Social and Human Aspects of Software Engineering [PDF]

, 2007
The people-intensive nature of software engineering has been understood for some time. Curtis et al [1] cite a number of studies in a variety of contexts demonstrating "the substantial impact of behavioural (i.e. human and organisational) factors on software productivity", while [2] believe that software companies are particularly vulnerable to people ...
openaire   +2 more sources

Software engineering whispers: The effect of textual vs. graphical software design descriptions on software design communication

Empirical Software Engineering, 2020
Software engineering is a social and collaborative activity. Communicating and sharing knowledge between software developers requires much effort. Hence, the quality of communication plays an important role in influencing project success.
Rodi Jolak, Maxime Savary-Leblanc, M. Dalibor, A. Wortmann, R. Hebig, Juraj Vincúr, I. Polásek, Xavier Le Pallec, S. Gérard, M. Chaudron   +9 more
semanticscholar   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Language engineering - a champion for European culture [PDF]

, 1996
Language is key to culture. It is a direct cultural medium as well as a means of recording and providing access to non-lingual elements of culture. Language is also fundamental to a sense of cultural identity.
Banus, E., Diver, J., Elio, B., Simpkins, N.   +3 more
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Psychological Safety and Norm Clarity in Software Engineering Teams

, 2018
In the software engineering industry today, companies primarily conduct their work in teams. To increase organizational productivity, it is thus crucial to know the factors that affect team effectiveness.
Bicchieri C., Choo A. S., Cialdini R. B., Delizonna L., Diegmann P., Duhigg C., Ellemers N., Festinger L., Flynn F. J., Meyers L. S., Sanner B., Schein E. H., Tavakol M., Van Dyne L.   +13 more
core   +1 more source

A Social Network Based Process to Minimize In-Group Biasedness During Requirement Engineering

IEEE Access, 2018
Evolution of social networking services has prompted a huge impact on major facets beyond the daily life of mankind. The Internet-based social media platforms are aiding us in numerous domains including healthcare, education, business, and software ...
Shuja Mughal, Assad Abbas, Naveed Ahmad, Samee U. Khan   +3 more
doaj   +1 more source

Hackathons as a Pedagogical Strategy to Engage Students to Learn and to Adopt Software Engineering Practices

Brazilian Symposium on Software Engineering, 2020
Teaching Software Engineering is not a trivial duty since several pedagogical strategies can be used and sometimes the impact of these on students is uncertain.
Caio Steglich, Larissa Salerno, T. Fernandes, S. Marczak, A. Dutra, A. Bacelo, Cássio Trindade   +6 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source