Results 101 to 110 of about 916,159 (305)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Company-university intersections through service-learning (SL): a systematic review

Frontiers in Education
The most relevant intersections in society include the relationship between universities and companies for a projection toward the sustainable employability of future graduates.
Margarita R. Rodríguez-Gallego, Rosario Ordóñez-Sierra, Soledad Domene-Martos, Cristina de-Cecilia-Rodríguez   +3 more
doaj   +1 more source

Sustainability Design and Software: The Karlskrona Manifesto [PDF]

Sustainability has emerged as a broad concern for society. Many engineering disciplines have been grappling with challenges in how we sustain technical, social and ecological systems.
Becker, Christoph, Chitchyan, Ruzanna, Duboc, Leticia, Easterbrook, Steve, Penzenstadler, Birgit, Seyff, Norbert, Venters, Colin   +6 more
core  

Embryomorphic Engineering: Emergent innovation through evolutionary development [PDF]

, 2014
Embryomorphic Engineering, a particular instance of Morpho-genetic Engineering, takes its inspiration directly from biological development to create new hardware, software or network architectures by decentralized self-assembly of elementary agents.
Dordea, Razvan, Doursat, René, Fourquet, David, Kowaliw, Taras, Sánchez Quintana, Carlos Alberto   +4 more
core  

Barriers for Social Inclusion in Online Software Engineering Communities - A Study of Offensive Language Use in Gitter Projects [PDF]

, 2023
Bastin Tony Roy Savarimuthu, Zoofishan Zareen, Jithin Cheriyan, Muhammad Yasir, Matthias Galster   +4 more
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

The role of social capital in promoting entrepreneurial readiness of engineering students at Shiraz University?

آموزش مهندسی ایران, 2017
The main objective of this study was checking the role of social capital in promoting entrepreneurial readiness of engineering students in Shiraz University. The method of this study was descriptive and correlational.
ghasem salimi, Mahboobe Mehrvarz, Reza Paziresh   +2 more
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Walking the line? The enactment of the social/technical binary in software engineering [PDF]

, 2009
Vivian Anette Lagesen, Knut H. Sørensen
openalex   +1 more source