Results 111 to 120 of about 1,317,898 (360)
Ambidextrous learning of engineering project team: Relying on control or BIM AI VR AR MR?
International Journal of Engineering Business Management, 2020 Through formal control and social control, technology platforms can acquire the information knowledge needed for ambidextrous learning of engineering project team, but whether technology platforms influence ambidextrous learning of engineering project ...
Suying Yang, Guiyun Cui, Shaokai Lu
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Revista Teknokultura, 2015 Reseña/Review (Gehl, R., "Reverse engineering social media: software, culture and political economy in new media capitalism", Philadelphia, PA: Temple University Press, ISBN 978-1-43991-035-1, 236 págs., 2014)
Javier de Rivera
doaj +2 more sources
Scientific AfricanThe objective of this study is to address the complex task of identifying optimal locations for reintroducing Ammotragus lervia in a semi-arid area in the Eastern High Atlas of Morocco, considering three topographical factors.
Lahbib Naimi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Programming Agents by Their Social Relationships: A Commitment-Based Approach
Algorithms, 2019 Multiagent systems can be seen as an approach to software engineering for the design and development of complex, distributed software. Generally speaking, multiagent systems provide two main abstractions for modularizing the software: the agents and the ...
Matteo Baldoni +3 more
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Barriers for Social Inclusion in Online Software Engineering Communities - A Study of Offensive Language Use in Gitter Projects [PDF]
, 2023 Bastin Tony Roy Savarimuthu +4 more
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Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source