Results 211 to 220 of about 1,317,898 (360)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Exploring Virtual Reality as a Tool for Enhancing Teaching and Learning Anatomy to Medical Students: A Feasibility and Acceptability Study. [PDF]

Clin Teach
Walsh A, O'Brien R, McGuire K, Power D.
europepmc   +1 more source

Social Engineering Exploits in Automotive Software Security: Modeling Human-targeted Attacks with SAM

, 2021
Matthias Bergler, Juha‐Pekka Tolvanen, Markus Zoppelt, Ramin Tavakoli Kolagari   +3 more
openalex   +2 more sources

Card games are effective tools to enhance foundation year health and safety inductions

FEBS Open Bio, EarlyView.
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq, Holly Matthews, Daniya Abedalreza, Faten Yahya, Matthew Allan Jones   +4 more
wiley   +1 more source

Sensitivity analysis of unsafe behaviors in the spinning and weaving factories: Exploring the association with burnout and resilience using Bayesian networks. [PDF]

PLoS One
Azimi R, Al Sulaie S, Yazdanirad S, Khoshakhlagh AH, Cousins R, Kazemian F.   +5 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Including frameworks of public health ethics in computational modelling of infectious disease interventions. [PDF]

Interface Focus
Zarebski A, Tellioglu N, Stockdale J, Spencer JA, KhudaBukhsh WR, Miller J, Zachreson C.   +6 more
europepmc   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey, Ahmad A. Toubasi, Jiacheng Wang, Habeeb F. Kazimuddin, Taegan Vinarsky, Caroline Gheen, Carynn Koch, Zachery Rohm, Bryan Hernandez, Margareta A. Clarke, Rachael Cheek, Rozita Khalili, Chaoyang Jin, Victoria Lim, John Kramer, Junzhong Xu, Ipek Oguz, Francesca Bagnato   +17 more
wiley   +1 more source

HRI-confusion: A multimodal dataset for modelling and detecting user confusion in situated human-robot interaction. [PDF]

Data Brief
Li N, Courtney J, Ross R.
europepmc   +1 more source

Social Foundations of a Software Design and Engineering Process.

, 2006
William A. Stubblefield, Tania Carson
openalex   +1 more source