Results 221 to 230 of about 1,372,389 (378)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Digital psychosocial follow-up for survivors of childhood critical illness: protocol for a systematic literature review. [PDF]

Syst Rev
Hagen MH, Jaccheri L, Papavlasopoulou S, Hartvigsen G, Sæter T.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Analyzing human factors affecting severe maternal morbidity (SMM) using fuzzy Bayesian network (FBN). [PDF]

Front Med (Lausanne)
Feiz-Arefi M, Laal F, Babaei-Pouya A, Mohammadi Darmiyan H, Pajohideh Z, Ajam A.   +5 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Geospatial tools in leprosy elimination: Enhancing precision in active case detection and resource allocation. [PDF]

PLOS Digit Health
Fastenau A, Gadah DAY, Bakoubayi AW, Gnossike P, Schwermann F, Willis M, Schlumberger F, Hambridge T, Vedithi SC, Stuetzle SCW, Deps PD, Ortuño-Gutiérrez N.   +11 more
europepmc   +1 more source