Results 231 to 240 of about 1,206,543 (334)

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

open access: yesAdvanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt   +10 more
wiley   +1 more source

Using personalised brain stimulation to modulate social cognition in adults with autism-spectrum-disorder: protocol for a randomised single-blind rTMS study. [PDF]

open access: yesBMC Psychiatry
Brouzou KO   +9 more
europepmc   +1 more source

Preventive Effect of Metformin in Radiation‐Induced Xerostomia

open access: yesAdvanced Biology, EarlyView.
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim   +5 more
wiley   +1 more source

Optimization of alumina leaching from microcline using particle swarm optimization and response surface methodology. [PDF]

open access: yesSci Rep
Nnanwube IA   +7 more
europepmc   +1 more source

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post‐Assembly Loading

open access: yesAdvanced Biology, EarlyView.
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati   +7 more
wiley   +1 more source

Finite element analysis of the lens profile during accommodation. [PDF]

open access: yesPLoS One
Schachar RA   +9 more
europepmc   +1 more source

Depletion of TP53 in Human Pluripotent Stem Cells Triggers Malignant‐Like Behavior

open access: yesAdvanced Biology, EarlyView.
Human pluripotent stem cells (hPSCs) with TP53‐depleting mutations are generated, mimicking commonly occurring events in vitro. Loss of TP53 does not alter pluripotency status or in vitro differentiation potential but causes genetic instability and transcriptome changes and confers superior clonal and anchorage‐free growth and higher chemotherapeutic ...
Joaquin Montilla‐Rojo   +9 more
wiley   +1 more source

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