In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt+10 more
wiley +1 more source
Using personalised brain stimulation to modulate social cognition in adults with autism-spectrum-disorder: protocol for a randomised single-blind rTMS study. [PDF]
Brouzou KO+9 more
europepmc +1 more source
An Architecture to Support Learning, Awareness, and Transparency in Social Software Engineering
Wolfgang Reinhardt, Sascha Rinne
openalex +2 more sources
Preventive Effect of Metformin in Radiation‐Induced Xerostomia
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim+5 more
wiley +1 more source
Optimization of alumina leaching from microcline using particle swarm optimization and response surface methodology. [PDF]
Nnanwube IA+7 more
europepmc +1 more source
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati+7 more
wiley +1 more source
Finite element analysis of the lens profile during accommodation. [PDF]
Schachar RA+9 more
europepmc +1 more source
Depletion of TP53 in Human Pluripotent Stem Cells Triggers Malignant‐Like Behavior
Human pluripotent stem cells (hPSCs) with TP53‐depleting mutations are generated, mimicking commonly occurring events in vitro. Loss of TP53 does not alter pluripotency status or in vitro differentiation potential but causes genetic instability and transcriptome changes and confers superior clonal and anchorage‐free growth and higher chemotherapeutic ...
Joaquin Montilla‐Rojo+9 more
wiley +1 more source
Risk and protective factors in academic burnout: exploring the mediating role of interpersonal emotion regulation in the link with social support. [PDF]
Messina I+4 more
europepmc +1 more source
CHI Madness Introduction Slide for the paper: Software Design and Engineering as a Social Process.
Tania Carson, William A. Stubblefield
openalex +1 more source