Results 111 to 120 of about 28,473,894 (313)

Spatial approach to sociological analysis of persons in somatic restrict conditions (review) [PDF]

open access: yesСаратовский научно-медицинский журнал, 2012
Research of socialization of persons in conditions of somatic restrictions is carried out within the limits of the spatial approach. Socialization is presented by the authors as rather independent fragment of social space — anthropogenous spaces.
Krom I.L.   +2 more
doaj  

THE TYPOLOGY OF REGIONAL IDENTITY OF THE POPULATION (ON THE EXAMPLE OF SAMARA REGION)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки, 2020
Background. In modern science, the concept of regional identity of the population is used to study the value system that characterizes the attitude of residents to the territory of residence.
I. V. Tsvetkova
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Measuring U-space social and environmental impact

open access: yes
U-space will enable urban air mobility (UAM) on a wide scale, facilitating a variety of use cases (e.g., medical and emergency transport, delivery of goods, passenger transport services).
Mocholí, David   +7 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Selected aspects of social space as the basis for understanding the »modernisation« of higher education [PDF]

open access: yesDružboslovne Razprave, 2018
Based on selected aspects of the social space, we establish a conceptual model for developing indicators of the »modernisation« of higher education systems.
Samo Pavlin
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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