Results 141 to 150 of about 6,063,141 (309)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Psicologia Escolar e EducacionalO presente estudo teve como objetivo caracterizar o comportamento de les de 295 estudantes do 6° ano da Escola Básica de instituições públicas e particulares em função do nível social.
Hermínia Vincentelli de Castillo +1 more
doaj
Social Status, the Spirit of Capitalism, and the Term Structure of Interest Rates in Stochastic Production Economies [PDF]
This paper studies capital accumulation and equilibrium interest rates in stochastic production economies with the concern of social status. Given a specific utility function and production function, explicit solutions for capital accumulation and ...
Heng-fu Zou, Liutang Gong, Yulei Luo
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Role of Coping Humour in the Physical and Mental Health of Older Adults [PDF]
Objectives - This study examined the associations among coping humor, other personal/social factors, and the health status of community-dwelling older adults. Method - Survey questionnaires were completed with 73 community dwelling older adults. Included
Elsa Marziali +2 more
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Self-supporting liberals and their cliques : an axiomatic characterization [PDF]
social groupssocial status;social ...
Dimitrov,D., Xu,Y.
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Pure Entertainment or Social Harmony? Understanding Private Returns to Social Spending on Household Ceremonies in China [PDF]
Recent social spending inflation in China has led to its growth rate far exceeding that of income and other consumption. In this paper, we estimate private returns to social spending, such as higher social status and larger social network that serve as ...
Chen, Xi
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source