Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Intersectional inequalities in childhood maltreatment and adolescent emotional problems in England: a random-coefficient MAIHDA analysis. [PDF]
Havers L +9 more
europepmc +1 more source
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Intersectional inequalities in COVID-19 morbidity and mortality in Sweden: a retrospective population-based cohort study. [PDF]
Honkaniemi H, Juárez SP.
europepmc +1 more source
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
Socio-Demographic Inequalities in COVID-19 Health Care Access and Experiences in the United Kingdom: Intersectional and Mixed-Methods Analyses of Open and Closed Questions in a Prospective Cohort Study. [PDF]
Cheetham NJ +6 more
europepmc +1 more source
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij +11 more
wiley +1 more source
Understanding depression through an intersectional framework: the joint impact of childhood adversities and social determinants using Canadian longitudinal study on aging (CLSA) data. [PDF]
Su Y, Li M, Fleury MJ, Adams GC, Meng X.
europepmc +1 more source

