Results 61 to 70 of about 73,887 (296)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Psychological Mediators of Social Inequalities in Health: Self-efficacy in Europe and Russia [PDF]

Социологический журнал, 2018
This study is devoted to psychologically mediating the social structuring of health. According to theoretical views, which have not yet received a convincing justification, the decline in the social status of an individual is accompanied by the loss of ...
Nina L. Rusinova, Viacheslav V. Safronov   +1 more
doaj   +1 more source

When individual action requires collective approval: a roadmap for solar power adoption by strata property owners

Purpose: This paper aims to examine a situation in which individual action requires collective approval – solar power adoption in strata properties – and offers a motivation-opportunity-ability theory-based model with which such a situation may be ...
Daly, M, Charters, B, Heffernan, T
core   +1 more source

The social gradient in smoking : individual behaviour, norms and nicotine dependence in the later stages of the cigarette epidemic

, 2022
The cigarette epidemic tends to develop in a similar pattern across diverse populations in different parts of the world. First, the prevalence of smoking increases, then it plateaus and finally it declines.
Östergren, Olof, Östergren, Olof,
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Depressive symptoms, education, gender and history of migration - an intersectional analysis using data from the German National Cohort (NAKO)

International Journal for Equity in Health
Background The educational gradient in depressive symptoms is well documented. Gender and history of migration have also been found to be associated with depressive symptoms.
Nico Vonneilich, Heiko Becher, Klaus Berger, Patricia Bohmann, Hermann Brenner, Stefanie Castell, Nico Dragano, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Lilian Krist, Berit Lange, Michael Leitzmann, Janka Massag, Claudia Meinke-Franze, Rafael Mikolajczyk, Nadia Obi, Tobias Pischon, Marvin Reuter, Börge Schmidt, Ilais Moreno Velásquez, Henry Völzke, Christian Wiessner, Olaf von dem Knesebeck, Daniel Lüdecke   +25 more
doaj   +1 more source

Social strata and it’s development of the Lithuanian population.

, 2010
The theoretical part of Master’s paper presents the concept of social stratification and analyzes social stratification theory. There is also presented the concept of social strata, distinguished main features of the social strata, based distribution to ...
Juodrienė, Lina,
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

SIGNIFIKANSI PENDIDIKAN MULTIKULTURAL TERHADAP KELOMPOK MINORITAS

Analisis, 2017
Indonesia as a nation of unity in diversity, composed of various ethnic groups, cultures, religions, social strata and others, is of course, in the hope of  harmony within diversities   in all terms of religion, politics, security, social class and as ...
Rahmawaty Rahim
doaj   +1 more source