Results 111 to 120 of about 146,954 (297)

The genomic footprint of social stratification in admixing American populations. [PDF]

Elife, 2023
Mas-Sandoval A, Mathieson S, Fumagalli M.   +2 more
europepmc   +1 more source

Educational Systems, Intergenerational Mobility and Social Segmentation [PDF]

We show that the very characteristics of educational systems generate social segmentation. A stylised educational framework is constructed in which everyone receives a compulsory basic education and can subsequently choose between direct working ...
Nathalie Chusseau, Joël Hellier
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Social Medicine Grand Rounds: A Collaborative Education Hub to Promote Action on Social Determinants of Health Across Community Sectors in Rural Alaska

Social Medicine, 2018
Background: The connection between social stratification and health inequalities in the United States suggests the need for medical education and practice to address social determinants of health as a key condition for achieving health equity.
Lucas Jacob Trout, Kristine Salters, Robert Inglis, Matthew Tobey, Jennifer Kasper, N. Stuart Harris   +5 more
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Societatea românească între polarizare şi stratificare. O perspectivă după 19 ani de postcomunism

Sociologie Românească, 2010
After nineteen years of postcommunism, Romania experiences a lot of changes in the social structure. The way from a social structure, which characterized the communist society, to a different kind of social structure which characterized a democratic ...
Bogdan Gheorghiță, Sabina-Adina Luca
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Intergenerational Social Mobility Among the Children of Immigrants in Western Europe: Between Socioeconomic Assimilation and Disadvantage

Sociological Science
Are Western European countries successfully incorporating their immigrant populations? We approach immigrant incorporation as a process of intergenerational social mobility and argue that mobility trajectories are uniquely suited to gauge the influence ...
Mauricio Bucca, Lucas G. Drouhot
doaj   +1 more source

Research on the healthy life expectancy of older adult individuals in China based on intrinsic capacity health standards and social stratification analysis. [PDF]

Front Public Health, 2023
Liu M, Zhang M, Zhou J, Song N, Zhang L.
europepmc   +1 more source