Results 71 to 80 of about 8,394,523 (323)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Social Stratification of Education by Ethnic Minority Groups over Generations in the UK
Social Inclusion, 2017 A large body of research has been conducted both on the social stratification of education at the general level and on the educational attainments of ethnic minority groups in the UK.
Laurence Lessard-Phillips, Yaojun Li
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
LEXICAL VARIATION IN THE CULTURAL SYNCRETISM OF JUM’AT KLIWONAN IN HB VII RELATIVES IN YOGYAKARTA SPECIAL TERRITORY [PDF]
, 2008 This research aims at describing 1) types of lexical variation used by HB VII relatives and kanca pethak in the event of Jum’at Kliwonan, 2) the relationship between lexical variation and palace culture and how those variations reflect the social ...
Siti Mukminatun, S.S., M.Hum.
core
RALPH DAHRENDORF’S CONFLICT THEORY OF SOCIAL DIFFERENTIATION AND ELITE THEORY [PDF]
Innovative Issues and Approaches in Social Sciences, 2013 Dahrendorf’s conception of social differentiation poses some interesting theoretical problems inasmuch as it, owing to its putative associations with Marx’s framework, is regarded as a class theory, but in fact displays also some salient characteristics ...
Jacek Tittenbrun
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
State University No More: Out-of-State Enrollment and the Growing Exclusion of High-Achieving, Low-Income Students at Public Flagship Universities [PDF]
, 2017 State flagship universities are facing an identity crisis. Will they continue a historic dedication to economic equity, or will they become instruments of social stratification?Although the admissions practices of private selective colleges are ...
Ozan Jaquette
core
Managing the Tensions of Essentialism: Purity and Impurity [PDF]
, 2012 This article proposes a new interpretation of Pierre Bourdieu, as a theorist of purity and impurity. Bourdieu’s writings indicate that through the adjudication of things or people as relatively impure or pure an image is constructed of their essential ...
Duschinsky, Robbie, Lampitt, Sue
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source