Results 101 to 110 of about 5,074,861 (337)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The Power of Social Cognition [PDF]

Journal of Social Structure, 2017
Geoffrey P. Morgan, Kenneth Joseph, Kathleen M. Carley   +2 more
doaj   +1 more source

House mouse subspecies do differ in their social structure. [PDF]

Ecol Evol, 2022
Mikula O, Macholán M, Ďureje Ľ, Hiadlovská Z, Daniszová K, Janotová K, Vošlajerová Bímová B.   +6 more
europepmc   +1 more source

A Comparative Social Policy Study on the Structure and Characteristic of Korean Welfare State - Focused on the Development of Public Social Expenditure -

, 2007
백승호, Sanghoon Ahn
openalex   +1 more source

Data for "Structure and drivers of social networks and their links with health in older adults"

, 2023
Cédric Sueur, Giovanna Fancello, Alexandre Naud, Yan Kestens, Basile Chaix   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

A Relational Hyperlink Analysis of an Online Social Movement [PDF]

Journal of Social Structure, 2011
Dean Lusher, Robert Ackland
doaj   +1 more source

Emergent social structure is typically not associated with survival in a facultatively social mammal. [PDF]

Biol Lett, 2023
Philson CS, Blumstein DT.
europepmc   +1 more source

La psychopathologie aux Antilles et ses relations avec les structures sociales

, 2015
M. Despinoy, A. Camelio
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source