Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Pinwheel Layout to Highlight Community Structure [PDF]
Bernie Hogan
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Radial Tree Diagram [RTD] of Insomnia [PDF]
Philip Topham
doaj +1 more source
Revealing the Hidden Social Structure of Pigs with AI-Assisted Automated Monitoring Data and Social Network Analysis. [PDF]
Agha S +5 more
europepmc +1 more source
Land Reform and Social Structure. A Sociohistorical Survey of the Impact of 1950’s Italian Land Reform on Property Relations and Class Formation in the Mezzogiorno [PDF]
Dana Dömșödi
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Using Visualizations to Explore Network Dynamics [PDF]
Kar-Hai Chu +2 more
doaj +1 more source
Intraspecific variability of social structure and linked foraging behavior in females of a widespread bat species (Phyllostomus hastatus). [PDF]
Calderón-Capote MC +3 more
europepmc +1 more source
How "Us" and "Them" Relates to Voting Behavior-Social Structure, Social Identities, and Electoral Choice. [PDF]
Bornschier S +3 more
europepmc +1 more source

