Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Behind the wall: Macrolithic artifacts as testing tools for activities and social structure on a Middle Chalcolithic site in Central Anatolia. [PDF]
Řídký J +5 more
europepmc +1 more source
An Analysis of the 'Failed States Index' by Partial Order Methodology [PDF]
Lars Carlsen, Rainer Brüggemann
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Social Structure in a Roma Settlement: Comparison over Time. [PDF]
Kozubik M +5 more
europepmc +1 more source
The influence of fish farm activity on the social structure of the common bottlenose dolphin in Sardinia (Italy). [PDF]
Frau S +5 more
europepmc +1 more source
If Parsons had Pajek: The Relevance of Midcentury Structural-Functionalism to Dynamic Network Analysis [PDF]
Benjamin Cornwell, Edward O. Laumann
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
A supergene-controlling social structure in Alpine ants also affects the dispersal ability and fecundity of each sex. [PDF]
De Gasperin O +8 more
europepmc +1 more source
The impact of social structure on breeding strategies in an island bird. [PDF]
McDonald GC +4 more
europepmc +1 more source

