Results 181 to 190 of about 5,111,635 (296)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

An Analysis of the 'Failed States Index' by Partial Order Methodology [PDF]

open access: yesJournal of Social Structure, 2013
Lars Carlsen, Rainer Brüggemann
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Social Structure in a Roma Settlement: Comparison over Time. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Kozubik M   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

A supergene-controlling social structure in Alpine ants also affects the dispersal ability and fecundity of each sex. [PDF]

open access: yesProc Biol Sci
De Gasperin O   +8 more
europepmc   +1 more source

The impact of social structure on breeding strategies in an island bird. [PDF]

open access: yesSci Rep, 2020
McDonald GC   +4 more
europepmc   +1 more source

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