Results 61 to 70 of about 5,111,635 (296)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Structure of Social Documents [PDF]

open access: yesProceedings of the Annual Hawaii International Conference on System Sciences, 2020
Susan P. Williams   +2 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Social Balance Theory: Revisiting Heider’s Balance Theory for many agents [PDF]

open access: yes
We construct a model based on Heider’s social balance theory to analyze the interpersonal network among social agents. The model of social balance theory provides us an interesting tool to see how a social group evolves to the possible balance state.
Deni Khanafiah, Hokky Situngkir
core  

Studying Social Networks at Scale: Macroscopic Anatomy of the Twitter Social Graph [PDF]

open access: yes, 2014
Twitter is one of the largest social networks using exclusively directed links among accounts. This makes the Twitter social graph much closer to the social graph supporting real life communications than, for instance, Facebook.
Gabielkov, Maksym   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Social Network Analysis on Food Web and Dispute Data [PDF]

open access: yes, 2016
Several social science disciplines, especially anthropology and sociology, have long engaged in social network analyses. Social Network Analysis (SNA) uses network theory to analyse social networks – a network that often involves individual social actors
Chiu, Grace   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Social status in a social structure: noisy signaling in networks [PDF]

open access: yes
How do incentives to engage in costly signaling depend on social structure? This paper formalises and extends Thorstein Veblen’s theory of how costly signaling by conspicuous consumption depends on social structure.
Tom Truyts
core  

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