Results 51 to 60 of about 1,287,849 (314)

Development and evaluation of the measurement properties of a generic questionnaire measuring patient perceptions of person-centred care

open access: yesBMC Health Services Research, 2020
Background Implementation of person-centred care (PCC) is a challenging undertaking. Thus, a call has been issued for a robust and generic instrument to measure and enable evaluation of PCC across settings and patient groups.
Helena Fridberg   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

How can social studies relate to youth civic engagement? Preparation for informed civic participation through an inquiry approach: The Singapore social studies curriculum

open access: yes, 2020
The term civic engagement is used in many different ways and a wide range of definitions can be found for the concept. Civic engagement can mean personal or collective action and it can include both political and nonpolitical participation.
Chee, Min Fui
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Regulation Implementation Effectiveness of Outdoors Users in Town Square of Bandung, Indonesia

open access: yesJournal of Contemporary Governance and Public Policy, 2020
Bandung Square in Indonesia is a public outdoors that has many visitors from various regions. One of the parts that make up Bandung town square is sign boards as a symbol of written rules that all square visitors must obey.
Harum Bunga Melati
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Exploring technology integration challenges and coping strategies among social studies teachers

open access: yesDiscover Education
In the 21st century, expectations for technology integration in education have increased, making it a necessity in international standards and updated curricula.
Muhammed Kürşat Öksüzoğlu   +1 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Cultural resilience study: the role of the temanten mandi ritual in Sendang Modo on the survival of the surrounding community

open access: yesCogent Arts & Humanities
Until now, the cultural values embodied in the traditions of the Javanese people have not been conclusively explained. The purpose of this research is to describe and explain the cultural value of the ritual of bathing rituals in Sendang Modo and its ...
Muhammad Hanif   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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