Results 241 to 250 of about 22,021,691 (406)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Influence of Social Support on Peri-Operative Pain: A Secondary Sub-Sample Analysis of a Prospective Observational Trial. [PDF]

Eur J Pain
Wenzel P, Gründahl M, Fischer M, Hein G, Fuchtmann F, Schnabel K, Rosenberger DC, Pogatzki-Zahn EM, Rittner HL, Teichmüller K.   +9 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Health and Social Support in the Aftermath of the Maui Wildfires.

JAMA Netw Open
Juarez R, Phankitnirundorn K, Ozorio Dutra SV, Bond-Smith D, Lee AG, Maunakea AK.   +5 more
europepmc   +1 more source

The impact of perceived social support on children's problem behaviors: the parallel mediating roles of attentional bias. [PDF]

BMC Psychol
Li Y, Zhu D.
europepmc   +1 more source

RELATIONSHIP BETWEEN PERCEIVED SOCIAL SUPPORTS FROM FAMILY AND FRIENDS, AND PSYCHOLOGICAL HEALTH IN COLLEGE STUDENTS

, 1995
Yoshiharu Fukuoka, Tsukasa Hashimoto
openalex   +2 more sources

Social Support, Depression, and Mortality During the First Year After Myocardial Infarction [PDF]

, 2000
Nancy Frasure‐Smith, François Lespérance, Ginette Gravel, Aline Masson, Martin Juneau, Mario Talajic, Martial G. Bourassa   +6 more
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Social Support, Negative Social Interactions, and Psychological Well‐Being [PDF]

, 2000
Karen D. Lincoln
openalex   +1 more source

Support for Youth Workers: Slipping on the Social Curve [PDF]

, 2009
Tan, John K E
core   +1 more source