Results 81 to 90 of about 1,952,808 (301)

Organizational culture, internal marketing, and perceived organizational support in portuguese higher education institutions [PDF]

open access: yes, 2018
Changes imposed on public higher education institutions try to adopt some management practices in public organizations. In this study, we intend to understand how organizational culture (support, innovation, goals, rules) and internal marketing can ...
Agasisti   +71 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modelo de integración de recursos para la atención de la salud mental en la población rural de México A model for integrating mental healthcare resources in the rural population of Mexico

open access: yesSalud Pública de México, 2003
OBJETIVO: Identificar conductas de utilización de servicios para resolver problemas de salud mental en los pobladores de localidades rurales de México; construir un modelo sobre los caminos de la atención para la salud mental que siguen los pobladores ...
V Nelly Salgado-de Snyder   +2 more
doaj  

Social support and sense of loneliness in solitary older adults [PDF]

open access: yes, 2017
Older people are vulnerable to loneliness and isolation. Solitary seniors are more likely to suffer the feelings of loneliness with inadequate social networks. Based on a face-to-face questionnaire survey with 151 community-dwelling solitary seniors, the
CT Veit   +12 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

THE INFLUENCE OF BINGE DRINKING ON SOCIAL SUPPORT NETWORKS

open access: yesSocial Work/Maatskaplike Werk, 2014
People and environments influence each other, negatively and positively. The abuse of alcohol affects any network negatively. The concepts “social support” and “networks” are described to demonstrate the interdependence and interrelatedness of systems ...
Marilyn Setlalentoa   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Social participation and depression among resettled Syrian refugees: examining a moderated mediation of social support and bonding or bridging social capital

open access: yesFrontiers in Psychology
IntroductionAspects of social capital, including social participation and social support, are among the factors influencing refugee mental health after resettlement.
Charisse M. Johnson-Singh   +6 more
doaj   +1 more source

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