Results 121 to 130 of about 1,512,127 (308)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Trees, Forests and PeopleAround the world, restoration activities are underway to halt and reverse ecosystem degradation. A key challenge is to identify restoration approaches that work for both people and nature – i.e.
Tom Reckmann +5 more
doaj +1 more source
Workforce sustainability in the Chilean logging sector : an ergonomics approach : a thesis presented in partial fulfilment of the requirement for the degree of Doctor of Philosophy in Management at Massey University, Albany, New Zealand [PDF]
, 2017 This thesis examines three key, related elements; social sustainability, forestry and ergonomics, and explores two relationships between these elements. The first relationship is between social sustainability and the Chilean forestry sector, with a focus
Meyer Cohen, Felipe
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Looking for the (missing) indicators of social sustainability - Evidence from sustainability standards in the coffe sector [PDF]
, 2010 Rising consumer interest for ethical and/or responsible products and the growing interweaving of social and environmental issues question the ability of scientific methods to correctly assess social impacts. To this day however, no consensus has yet been
Lemeilleur, Sylvaine, Vagneron, Isabelle
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Promotion sustainable tourism in global economy [PDF]
, 2018 Purpose is to substantiate the ways of promotion sustainable tourism in the global economy. Methodology - To determine the importance of the sustainable tourism factors, the hierarchy analysis method of T. Saati was used.
Krasnikova, Nataliya +3 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The Impact Of Shopping Tourism In Surabaya [PDF]
, 2011 Tourism is a key sector for the economic development of a city. The local government develops tourism in accordance with its potential. However, the development of tourism needs to consider the sustainability of the related industry in the area, as the ...
Andajani, Erna +2 more
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