Results 31 to 40 of about 13,235 (262)

Expert vs. Novices Dimensions of Tagging Behaviour in an Educational Setting

open access: yesBilgi Dünyası, 2012
The organization and representation of information and knowledge have always been exclusively in the domain of professionals and experts. This has begun to change with the development of folksonomies as alternative, user-generated models of organizing ...
Sonja Spiranec, Mislav Borovac
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Digital Exhibition and Keyimage Ontology

open access: yesBilgi Dünyası, 2008
The Age of Image predates and is currently contemporaneous with the Information Age. In our times the explosive expansion of Web 2.0 Social Space, typified by the phenomena of De.licio.us, Flickr, MySpace, YouTube…, and the concomitant emergence of ...
Mícheál Mac an Airchinnigh   +1 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Exploring Social Relations for Personalized Tag Recommendation in Social Tagging Systems

open access: yesIEICE Transactions on Information and Systems, 2011
With the emergence of Web 2.0, social tagging systems become highly popular in recent years and thus form the so-called folksonomies. Personalized tag recommendation in social tagging systems is to provide a user with a ranked list of tags for a specific resource that best serves the user's needs. Many existing tag recommendation approaches assume that
LIU, Kaipeng   +2 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Perkembangan Dan Pembelajaran Bahasa Anak Menuju Bahasa Mitos

open access: yesINSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2015
: The development pattern of a child into the identity not only formed through psychological symptoms, but there are various relationships that shape it.
Arif Hidayat
doaj   +3 more sources

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