Results 111 to 120 of about 22,592,949 (347)
História, Ciências, Saúde: Manguinhos, 2005 O artigo empreende uma análise sobre a imagem da mulher amazônica na representação que dela faz Elizabeth Agassiz em Viagem ao Brasil: 1865-1866, obra editada na Europa em 1867, com base no diário da expedição científica Thayer, dirigida pelo naturalista
Fabiane Vinente dos Santos
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Mental Simulations of Social Thought and Action
, 2011 Could simply imagining positive interactions promote tolerance between different social groups? This imagined contact hypothesis (Crisp & Turner, 2009) is just one example of a range of psychological interventions that capitalize on people’s capacity for
R. Crisp, M. Birtel, Rose Meleady
semanticscholar +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Science and Ideology in Economic, Political, and Social Thought [PDF]
, 2006 This paper has two sources: One is my own research in three broad areas: business cycles, economic measurement and social choice. In all of these fields I attempted to apply the basic precepts of the scientific method as it is understood in the natural ...
Claude Hillinger +2 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The “Plandemic” Emojis, Conspiracy Theories and Online Hate Micro-narratives on Twitter
Culture e Studi del SocialeAlthough social science research on COVID-19 is diverse, few studies have focused specif-ically on emojis. Similarly, research that has paid attention to emojis from a social network analysis perspective is almost non-existent.
Estrella Gualda
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