Results 111 to 120 of about 3,635,145 (314)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Catholic Social Thought Concerning the Right to Health and to Health Care. [PDF]
Linacre Q, 2020 Buckley LF.
europepmc +1 more source
How to make social cohesion work. Bertelsmann Stiftung Speech 2019 [PDF]
, 2019 The megatrends of globalization and digitalization pose challenges for social cohesion. Many people are concerned about their economic future, and right-wing populists are leveraging the internet to spread oversimplified messages and fuel fears.
Saul, John Ralston
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Etherotopia or a country in the mind: bridging the gap between utopias and nirvanas [PDF]
, 2015 Joyce Hertzler concludes his History of Utopian Thought with the phrase ‘Utopia is not a social state it is a state of mind’. Other utopian scholars would argue that the truth is exactly the opposite, that utopia is a purely social matter. There seems to
Callow, Christos Jr
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Reflecting on the notion of difference and sense of identity of a Spanish-born Chinese youth and her family. A biographical narrative approach [PDF]
, 2017 This paper is based on a biographical research focus on a clearer understanding of socio-cultural difference represented by migrants and their descendants in our western society and the multifaceted social interactions and experiences that influenced ...
Mancila, Iulia
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source