Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Agreeing to disagree: When do superordinate identities facilitate competing opinion-based groups to work through intergroup conflict? [PDF]
Haines EA, Thomas EF, Wenzel M.
europepmc +1 more source
Cross-Cultural Marital Satisfaction: Individualistic and Collectivist Influences. [PDF]
Aflatooni L, Daneshpour M.
europepmc +1 more source
Is It a Just World After All? Age Differences in the Belief in a Just World Across 57 Societies and the Influences of Cultural Values. [PDF]
Li T, Guo N, Luo W.
europepmc +1 more source
Current status and associated factors of social avoidance in postoperative breast cancer patients: a cross-sectional study. [PDF]
Chen X +7 more
europepmc +1 more source
To Possess or to Experience: Personal Values and Sociocultural Context Moderated Age Differences in Purchase Evaluations. [PDF]
Peng H, Li T.
europepmc +1 more source
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