Results 71 to 80 of about 1,605,555 (314)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2014 To make education a profitable enterprise and contributor to social development in the age of globalisation a strong role of the school in values integration and as part of the ethical construction of learners and citizenship building A mixed design ...
M.M. (Nonnie) Botha, Denis Sekiwu
core
Basic human values: Inter-value structure in memory
, 2007 Three experiments examined the latent structure of values. Participants rated the importance of values clustered in pairs. Based on [Schwartz, S. H. (1992). Universals in the content and structure of values: Theoretical advances and empirical tests in 20
Maio, Gregory +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Concepts of ‘Social Value Creation’ and ‘Social Value’
, 2016 This chapter explores the concept of ‘social value’ from the perspectives of both social entrepreneurs and the beneficiaries. All social entrepreneurs see ‘social value creation’ in bringing social change or creating social impact (long term impact)/outcomes (immediate or short term impact), while addressing social problems/issues/needs.
openaire +1 more source
Judgment and Decision Making, 2013 Prior research on self-other differences involving risk have found that individuals make riskier decisions for others than for the self in situations where risk taking is valued.
Eric R. Stone +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2009 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Social work struggles between the dichotomy of “individual” and “society” as it is characterized as enhancing both individual well-being and social justice.
Giannou, Dimitra
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source