Results 241 to 250 of about 41,694 (345)

A Novel Cell‐Penetrating Lipopeptide for DNA Binding, Self‐Assembly, and Delivery Into HeLa and Pluripotent Stem Cells

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
A lipopeptide is designed that contains an epitope from simian virus T‐antigen (SV40T, PKKKRKV) conjugated to an N‐terminal palmitoyl (C16‐) moiety, which acts as a cell‐penetrating lipopeptide, with additional aggregation propensity conferred by the lipid chain. The lipopeptide enables DNA delivery into the cytoplasm and nucleus.
Lucas R. de Mello   +6 more
wiley   +1 more source

Learning Covariate Relations in Disease Progression Models Using Symbolic Neural Networks

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Covariate modeling provides individual predictions of outcomes by disease progression models. Current methodology for mapping covariates onto model parameters is limited by predefined parametric functions which can result in inadequate covariate selection and biased predictions by the final model. Furthermore, present methodology scales poorly
Jesper Sundell   +4 more
wiley   +1 more source

Working 9 to 5: Diurnal Variability in Terrestrial Invertebrate Activity Does Not Compromise Ecosystem Health Assessments in Dry Stream Channels

open access: yesRiver Research and Applications, Volume 42, Issue 3, Page 676-688, March 2026.
ABSTRACT Temporary streams are impacted by climate change and other anthropogenic pressures, but fluctuating water levels complicate ecological assessments. Terrestrial invertebrate communities may enable dry‐phase assessments, but their sampling can be resource intensive.
Kieran J. Gething   +6 more
wiley   +1 more source

A Modelling Framework to Estimate Vector Dispersal and Disease Spread in an Important Agricultural Pathosystem

open access: yesJournal of Sustainable Agriculture and Environment, Volume 5, Issue 1, March 2026.
A model of aphid‐vectored BYDV highlights the importance of the interaction between aphid and viral genetic and species diversity on the risk presented by crop disease. The modelling framework offers a tool to explore vector–virus–host interactions and both conventional and natural controls in a spatial context.
Katharine F. Preedy   +5 more
wiley   +1 more source

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