Results 91 to 100 of about 1,195,997 (308)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Public–private partnerships and human development
International Journal of Management and EconomicsThe restructuring of a state is crucial for promoting human development. For this reason, public–private partnerships (PPPs), the so-called “fourth revolution” in reinventing the state, have become a global strategy of choice.
Hanna Kociemska +2 more
doaj +1 more source
An Analysis of the Impact of China's Population Structure Changes on Social Welfare System
Journal of Economics and LawPopulation structure refers to the distribution of population in a country or region based on indicators such as gender, age, occupation, and education level. With the development of Chinese society and changes in the economy, the population structure has also undergone changes, which have had a profound impact on the welfare system of Chinese society.
openaire +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
On the impact of digital music distribution [PDF]
We present a framework to evaluate the impact of digital music distribution. We set up a representative model that enables the comparative static analysis.
Yoon, Kiho
core
Welfare Participation by Immigrants in the UK [PDF]
, 2011 Welfare participation is an important indicator of how successfully immigrants perform in the host country. This paper examines this issue for the UK, which has experienced a large growth in its immigrant flows and population levels in recent years ...
Catherine Robinson, Stephen Drinkwater
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Croatian Accession to the European Union: Facing the Challenges of Negotiations [PDF]
The paper discusses aspects of Croatian social policy, particularly social inclusion and social dialogue, in the context of Croatia’s status as a candidate country for accession to the EU.
Katarina Ott +2 more
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source