Results 81 to 90 of about 1,195,997 (308)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Poverty, Inequality and the Role of Social Grants: An Analysis using Decomposition Techniques [PDF]

open access: yes
Despite South Africa’s transition from apartheid in 1994, the social landscape is still fragmented along racial lines. However, South Africa has an impressive social grants system by international standards, with social assistance spending as a ...
Cobus Burger, Paula Armstrong
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Health Adjusted GDP (HAGDP) Measures of the Relationship Between Economic Growth, Health Outcomes and Social Welfare [PDF]

open access: yes
Welfare economic analysis of health issues and policies can provide well balanced orderings of the state of the economy. This paper provides an innovative framework for welfare economic analysis of the relationships between economic growth, health ...
Matthew Clarke, Sardar M. N. Islam
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Welfare consequences of a recent tax reform in Mexico [PDF]

open access: yes
This paper evaluates the indirect tax reforms that took place in México in 1995 and 1998, focusing on their impact on welfare at the household and social levels.
Carlos M. Urzúa
core  

Mixed duopolies with advance production [PDF]

open access: yes, 2013
Production to order and production in advance has been compared in many frameworks. In this paper we investigate a mixed production in advance version of the capacity-constrained Bertrand-Edgeworth duopoly game and determine the solution of the ...
Balogh, Tamás László   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Social welfare and economic equality: healthcare expenditure as a moderator

open access: yesFrontiers in Public Health
IntroductionThis study aims to examine the impact of social welfare expenditure on household economic equality, as well as the moderating effect of healthcare expenditure on this relationship.
Gai Liu
doaj   +1 more source

The Impact of Vertical R&D Cooperation on Market Performance of Firms

open access: yesEntrepreneurial Business and Economics Review, 2019
Objective: The aim of this article is to investigate the impact of vertical R&D cooperation on market performance of firms. Specifically, we explore the impact of vertical R&D cooperation on firms’ process innovation, outputs, market prices, and
Adam Karbowski, Jacek Prokop
doaj   +1 more source

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