Results 131 to 140 of about 2,991,289 (316)

Family support and child protection approaches : historicising perspectives on contemporary discourses of social work

open access: yes, 2018
This paper examines the impact of two prevailing and seemingly opposed ideologies in child welfare in Western societies over the last century (‘family support’ and ‘child protection’) on social work practice.
Verhallen, Tessa,   +6 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

2008 Agenda: The 20th National Symposium on Doctoral Research in Social Work

open access: yes, 2008
The University Archives has determined that this item is of continuing value to OSU's ...
Ohio State University. College of Social Work
core  

Drug Abuse from Social Work Perspectives

open access: yes
Social work plays a crucial role in restoring societal functions. This paper advocates for integral theory as a defining framework for the identity of social work.
Singh, Paramjit Singh Jamir   +4 more
core   +1 more source

Peer Relationships and Social Work Practice in Canadian Hospitals

open access: yes, 2020
This masters’ thesis is a modest exploratory study which seeks to better understand social work peer relationships among front line workers in Canadian hospitals.
Bryksa, Erin
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Probabilistic Record Linkage for Families (PRLF): A Discussion of the Development and Validation of this Open-Source Linkage Tool

open access: yesInternational Journal of Population Data Science
Linking administrative records across programs can yield person-centered information, including client characteristics, public service trajectories, and outcomes and help to answer policy-related questions.
John Prindle   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

“Live Social Work” : How to Bring Life Back into Social Work

open access: yes, 2015
In this article I discuss how professional social work can entail critical, reflexive work. This is accomplished by adapting the concept of “live sociology”.
Herz, Marcus
core  

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