Results 131 to 140 of about 860,977 (325)
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Intersexués : le troisième genre en question en France et au-delà
Socio, 2017 All societies know the binary classification of gender which consists in classifying the individuals as man or woman, with the exception of certain societies which recognize the existence of a third gender.
Corinne Fortier
doaj +1 more source
Uniqueness of Medical Data Mining: How the new technologies and data they generate are transforming medicine [PDF]
arXiv, 2019 The paper describes how the new technologies and data they generate are transforming medicine. It stresses the uniqueness of heterogeneous medical data and the ways of dealing with them. It lists different sources that generate big medical data, their security, legal and ethical issues, as well as machine learning/AI methods of dealing with them.
arxiv
Future research demands of the United European Gastroenterology (UEG) and its member societies [PDF]
, 2019 AIMS: The purpose of this study was to initiate and stimulate collaborative research efforts to support United European Gastroenterology Federation (UEG) member societies facilitating digestive health research in European on the one hand and, on the ...
Acedo, P +15 more
core
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
History of Key Events in Women’s Health Care
, 2016 In 1973, ninety-three percent of all American doctors were men (Ehrenreich and English). Gender based inequity permeates all spheres of women’s health care from employment to access to treatment to biologically-based myths of male superiority, yet women ...
Chambliss, Zoё M.
core