Results 41 to 50 of about 7,550,915 (348)

Recent Update of Guidelines for Neurointerventional Procedures [PDF]

Neurointervention, 2013
Treatment guidelines of the neurointerventional procedures are continuously updated. However, these guidelines differ between countries and even medical societies within the same country because of the differing interests and patient groups.
Shang Hun Shin, Soon Chan Kwon, Dae Chul Suh   +2 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Opioid Exposed Mothers and Infants in Delaware: Clinical and Legal Considerations [PDF]

, 2016
Drug use is on the rise in Delaware, as demonstrated by the continued increase in infants born with neonatal abstinence syndrome. Thoughful, evidence based, and coordinated approaches are necessary to impact this problem.
Paul, MD, David A., Savin, MSN, NNP-BC, Michele K.   +1 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).

Europace, 2010
Guidelines summarize and evaluate all currently available evidence on a particular issue with the aim of assisting physicians in selecting the best management strategy for an individual patient suffering from a given condition, taking into account the ...
A. Camm, P. Kirchhof, G. Lip, U. Schotten, I. Savelieva, S. Ernst, I. V. Van Gelder, N. Al-Attar, G. Hindricks, B. Prendergast, H. Heidbuchel, O. Alfieri, A. Angelini, D. Atar, P. Colonna, R. de Caterina, J. De Sutter, A. Goette, B. Gorenek, M. Heldal, Stefan H. Hohloser, P. Kolh, J. Le Heuzey, P. Ponikowski, F. Rutten, A. Vahanian, A. Auricchio, Jeroen J. Bax, C. Ceconi, V. Dean, G. Filippatos, C. Funck-Brentano, Richard Hobbs, P. Kearney, T. McDonagh, B. Popescu, Željko Reiner, U. Sechtem, P. Sirnes, M. Tendera, P. Vardas, Petr Widimsky, V. Agladze, E. Aliot, T. Balabanski, C. Blomstrom-Lundqvist, A. Capucci, H. Crijns, B. Dahlöf, T. Folliguet, M. Glikson, M. Goethals, D. Gulba, S. Ho, R. Klautz, S. Kose, John Mcmurray, Pasquale Perrone Filardi, P. Raatikainen, M. J. Salvador, M. Schalij, A. Shpektor, J. Sousa, J. Stȩpińska, H. Uuetoa, J. Zamorano, I. Zupan   +66 more
semanticscholar   +2 more sources

Current context and evaluation of medical residency programs: experience of six Brazilian Medical Societies [PDF]

Revista do Colégio Brasileiro de Cirurgiões
This article shows the most recent data on the evolution of the number of resident physicians and vacancies from R1 to R5, as well as the number of programs and institutions accredited by the National Commission for Medical Residency (CNRM).
GERSON ALVES PEREIRA JÚNIOR, RAMIRO COLLEONI NETO, JAIR GIAMPANI JÚNIOR, JORGE CARVALHO GUEDES, REGINALDO RAIMUNDO FUJITA, ADRIANO FERNANDO MENDES JÚNIOR, GUSTAVO SALATA ROMÃO, LUCAS NEPOMUCENO BARROS, LUIZ ALONSO DAVID, PAULO FERNANDO CONSTANCIO DE SOUZA, JOSÉ EDUARDO LUTAIF DOLCI, CESAR EDUARDO FERNANDES   +11 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

The flight of the white collars [PDF]

, 2013
By analyzing two novel data sets from Turkey, we provide empirical evidence for yet another negative consequence of civil conflicts. We show that the long running civil cinflict in Turkey has been driving away doctors and other medical personnel from ...
Kıbrıs, Arzu, Kibris, Arzu
core  

Adapting health care institutions and medical schools to societies' needs.

Academic medicine : journal of the Association of American Medical Colleges, 1999
Although societies and the priorities of stakeholders within them differ, four universal values regarding health care exist: quality, equity, relevance, and cost-effectiveness.
C. Boelen
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source