Results 51 to 60 of about 846,883 (273)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Recommendations of the EANS Global and Humanitarian Neurosurgery Committee for sustainable neurosurgical partnerships in low-resource settings

Brain and Spine
Background: Despite growing interest in global neurosurgery, equitable access to neurosurgical care in low- and middle income countries (LMICs) remains limited.
Nicolò Marchesini, Vicki M. Butenschoen, Andreas K. Demetriades, Said Idrissa Ahmada, Kostantinos Gousias, Fazlul Hoque, Thomas Kapapa, Patrick D. Kamalo, Pablo González-López, Jesus Lafuente, Nigel Mendoza, Rupavathana Mahesperan, Wouter A. Moojen, Vincenzo Paternò, Ondra Petr, Wilco C. Peul, Lukas Rasulic, Nicephorus Boniface Rutabasibwa, Jamil Rzaev, Ellianne J. dos Santos Rubio, Abenezer Tirsit Aklilu, Jake Timothy, Massimiliano Visocchi, Oleksandr Voznyak, Enoch O. Uche, Magnus Tisell   +25 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

ASH choosing wisely [PDF]

, 2014
The Choosing Wisely(R) campaign challenges medical societies to identify 5 tests, procedures, or treatments within each specialty's clinical domain that are offered to patients despite an absence of evidence demonstrating benefit or, in some cases ...
Arya, Monika, Kodali, Murali, Nistala, Puja   +2 more
core  

Implementation of a point-of-care ultrasound skills practicum for hospitalists [PDF]

, 2019
Introduction Point-of-care ultrasound is recognized as a safe and valuable diagnostic tool for patient evaluation. Hospitalists are prime candidates for advancing the point-of-care ultrasound field given their crucial role in inpatient medicine. Despite
Carlos, W. Graham, Cochard, Emily, Fulkerson, Zachary   +2 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

THE ROLE OF PEDIATRICIANS IN CARING FOR THE WELL-BEING OF CHILDREN LIVING IN NEW TYPES OF FAMILIES

Педиатрическая фармакология, 2017
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Pietro Ferrara, Giovanni Corsello, Annamaria Sbordone, Costanza Cutrona, Jochen Ehrich, Massimo Pettoello-Mantovani   +5 more
doaj   +2 more sources

A searchable database of medical education objectives – creating a comparable gold standard

BMC Medical Education, 2018
Background Medical school curricula strives to teach as much material as can be retained in a limited amount of time. A common “gold standard” resource used building curricula are medical objectives suggested by national societies.
Sam Brooks, Namita Biala, Sage Arbor
doaj   +1 more source

Conservative management of low back pain [PDF]

, 2001
Back pain is prevalent worldwide, but back pain disability has reached epidemic proportions in many industrialised societies. Few patients have serious medical pathology or direct neurological involvement requiring surgery.
De Souza, LH, Frank, AO
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source