Results 81 to 90 of about 6,162,683 (250)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Medical College building, 1914

, 1914
This glass lantern slide features a ground view of the Medical College Building of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Medical College court, 1950

, 1950
This glass lantern slide features an aerial view of the Medical College of the State of South Carolina court in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Medical societies and patient-centered communication: A review of current practices and future directions

Continence Reports
Introduction: Patient-centered communication (PCC) is a vital component of high-quality medical care, fostering respectful, responsive interactions that align clinical decisions with patient values.
Filippos Nikitakis, Aikaterini Tsionga, Vasileios Tatanis, Konstantinos Gkialas, Ioannis Glykas, Markos Karavitakis, Theodoros Paizis, Christos Roidos, Theodoros Spinos, Christos Zampaftis, Michael Samarinas   +10 more
doaj   +1 more source

Northwestern University Survey of Woman's Medical School Alumnae: Class of 1871.

, 1914
Northwestern University Surveys of Woman's Medical School of Chicago Alumnae for the class of 1871, which were collected in 1914. These surveys contain the alumna's name, place and date of birth, education, hospital appointments, membership of medical ...

core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Northwestern University Survery of Woman's Medical School Alumnae: Class of 1879.

, 1914
Northwestern University Surveys of Woman's Medical School of Chicago Alumnae for the class of 1879, which were collected in 1914. These surveys contain the alumna's name, place and date of birth, education, hospital appointments, membership of medical ...

core