Results 81 to 90 of about 855,704 (293)

Medical advice-seeking behaviors based on transaction cost theory

Cost Effectiveness and Resource Allocation, 2018
Background Given the global trend of aging societies, medical expenditure has hit record highs in many countries. Because medical advice-seeking behaviors can affect the health of whole societies, how members of a society make medical-related decisions ...
Shih Han Lin, Tom M. Y. Lin
doaj   +1 more source

Evaluation of recovery after intravenous sedation [PDF]

, 2017
The Intravenous Sedation (IVS) Guideline Working Group of the Japanese Dental Society of Anesthesiology (JDSA) formulated guidelines for intravenous conscious sedation in dentistry.
Fujisawa, Toshiaki, Shibuya, Makiko
core  

Male and female emirati medical clerks’ perceptions of the impact of gender and mobility on their professional careers [PDF]

, 2017
Background: Medicine has undergone profound changes in terms of the number of women entering the profession with postulated implications of this ‘feminization’ for the profession.
Higgins-Opitz, Susan B., McLean, Michelle   +1 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Trends of Representation of Women in Professional Medical Societal Leadership in the United States and Europe

JACC: Advances
Background: There continue to be significant gender disparities with women being underrepresented in medical professional society leadership roles, despite more women entering medical school.
Sherna B. Menezes, MBBS, Ashleigh N. Shenton, MD, Allison G. Hays, MD, Cynthia C. Taub, MD, MBA   +3 more
doaj   +1 more source

Just shamans and healers or indigenous medical systems? A critical discourse analysis of the categories of shamans and healers as constructed by social science texts [PDF]

"Just as even a single sentence has traditionally been taken to imply a whole language so a single discourse implies a whole society." Language and Power, N. Fairclough.
Moreno-Leguizamon, Carlos
core  

The Politics of Vodou: Aids, Access to Health Care and the Use of Culture in Haiti [PDF]

, 2007
During the past few years, the AIDS campaign in Haiti has been targeting Vodou officiants and organizations. These awareness and training programmes in- form officiants about the transmission and prevention of AIDS, tests for HIV and anti- retroviral ...
Benoît, Catherine
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

How Should Clinicians Weigh the Benefits and Harms of Discussing Politicized Topics that Influence Their Individual Patients\u27 Health? [PDF]

, 2017
Health implications of politically charged phenomena are particularly difficult for physicians to discuss with their patients and communities. Addressing climate change and its associated health effects involves trade-offs between health and economic ...
Alame, Diana, Truog, Robert D.
core   +1 more source