Results 231 to 240 of about 3,967,313 (340)

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

Angewandte Chemie, EarlyView.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng, Daisuke Noshiro, Shiroh Futaki, Ryuji Kawano   +3 more
wiley   +2 more sources

Design of a Pharmaceutical Protocol for the Evaluation of Phytotherapeutic Products. [PDF]

Farm Comunitarios
Parra-Astorgano L, Prats Mas R, Villegas Lama I, Busto Domínguez I, Morales Marrero C, Roig Marín-Yaseli M, López Gil J.   +6 more
europepmc   +1 more source

Dabigatran Concentrations in an Actively Breastfeeding Mother–Infant Dyad: Extending the Evidence for Oral Thromboprophylaxis Postpartum

American Journal of Hematology, Volume 101, Issue 7, Page 1628-1631, July 2026.
Rasmus W. Green, Aljona Saleh, Pawel Baranczewski   +2 more
wiley   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

DNA‐Induced Entropic Gain Triggers an Allosteric Switch for Biomolecular Condensation of Heat Shock Transcription Factor 1

Angewandte Chemie, EarlyView.
Hsf1 undergoes phase separation around target DNA, activating stress‐responsive transcription. DNA binding tunes conformational dynamics of Hsf1DBD, which propagates through large‐scale domain rearrangements involving DBD–IDR interactions to regulate phase separation. This hierarchical framework illustrates how local structural events at the side chain
Soichiro Kawagoe, Hiroyuki Kumeta, Tomohide Saio   +2 more
wiley   +2 more sources

Health promotion at the crossroads: putting civil society in the driver's seat. [PDF]

Health Promot Int
Shiroya V, Bost T, Kadasia B, Sozanski G.   +3 more
europepmc   +1 more source

Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

American Journal of Hematology, EarlyView.
Astrid Hundebøll Torpe, Jonathan Thorsen, Gustav Mathiasen, Katrine Fladeland Iversen, Sarah Farmer, Thomas Lund, Charlotte Toftmann Hansen, Lene Kongsgaard Nielsen, Nicolai Grønne Dahlager Jørgensen, Maja Ølholm Vase, Elena Manuela Teodorescu, Morten Salomo, Christina Wennerström, Tobias S. Slørdahl, Agoston Gyula Szabo   +14 more
wiley   +1 more source

Cyclo‐Polyproline: Chameleonic All‐Peptide Macrocycles With Induced‐Fit Host‐Guest Recognition

Angewandte Chemie, EarlyView.
Macrocycles served as the genesis of supramolecular chemistry, advancing synthetic, separation, and materials fields. Despite their utility, they typically lack synthetic control. This work establishes a robust platform for all‐peptide macrocycles capable of host‐guest complexation and chameleonic behavior.
Camilla Di Girolamo, Patricia C. Fleming, Caroline R. Kwawu, Amanda R. Guimarães, Jimmy Muldoon, Julia Bruno‐Colmenarez, Yannick Ortin, Michael R. Probert, Felipe Fantuzzi, Aniello Palma   +9 more
wiley   +2 more sources

Overmedicalisation of childhood: what paediatricians and child health professionals <i>can</i> <b>do</b>. [PDF]

BMJ Paediatr Open
Liao L, Teoh Y, Ghosh S, Jain M, Marder L, Turner S, Raman S.   +6 more
europepmc   +1 more source