Results 101 to 110 of about 529,326 (314)

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Determinantes do hábito de fumar e de seu abandono durante a gestação em localidade urbana na região sul do Brasil

Revista de Saúde Pública
Foi realizado um estudo transversal, com 873 gestantes que freqüentaram o pré-natal em Pelotas (RS), em 1989-90, com o objetivo de investigar possíveis fatores de risco e fatores prognósticos para o tabagismo durante a gravidez.
Iná S. Halal, Cesar G. Victora, Fernando C. Barros   +2 more
doaj  

Spatial and Socioeconomic Factors Influencing Labor Force Participation Rates [PDF]

, 1982
Roger J. Beck, J. Dean Jansma
openalex   +1 more source

A Dynamic DNA Nano‐Antioxidant Targeting Galectin‐3 Attenuates Liver Fibrosis via Reducing Macrophage Oxidative Stress

Advanced Science, EarlyView.
This study developed a dynamic DNA nano‐antioxidant (DDN) for Galectin‐3 siRNA delivery, specifically targeting hepatic macrophages to suppress ROS‐driven fibrosis. DDN enhanced hepatic accumulation, restored NRF2 signaling, and attenuated oxidative stress, collagen deposition, and fibrotic progression in a CCl4‐induced cirrhosis model, demonstrating ...
Mengjia Peng, Jianguo Xu, Youjian Hong, Fei Fang, Yan Li, Duo Ci, Bowen Wang   +6 more
wiley   +1 more source

Scalable Lignin Monomer Production Via Machine Learning‐Guided Reductive Catalytic Fractionation of Lignocellulose

Advanced Science, EarlyView.
This study pioneers an integrated machine learning framework combining large‐scale data modeling, experimental validation, and impact analysis to optimize reductive catalytic fractionation for scalable, sustainable lignin monomer production. Abstract Efficient valorization of lignocellulosic biomass into high‐value lignin monomers is a cornerstone of ...
Meysam Madadi, Ehsan Kargaran, Seyed Sajad Hashemi, Chihe Sun, Joeri F.M. Denayer, Keikhosro Karimi, Fubao Sun, Vijai Kumar Gupta   +7 more
wiley   +1 more source

Socioeconomic factors and cardiovascular disease: a review of the literature. [PDF]

, 1993
George A. Kaplan, Julian Keil
openalex   +1 more source

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Rattan‐Based Solar Evaporator Hits 3.34 Kg·M−2·h−1 and Long‐Term Salt Resistance via Programmed Carbonization

Advanced Science, EarlyView.
A rattan‐based evaporator with bimodal hierarchical porous structures achieves an high evaporation rate of 3.34 kg m−2 h−1 under 1 sun illumination by optimizing the surface water layer, localizing heat, and reducing vaporization enthalpy. Abstract Global water scarcity urgently demands sustainable purification solutions.
Shanshan Jia, Xiaqing Qin, Shijie Dai, Yan Qing, Jianwu Dai, Shaobo Zhang, Hui Xiao, Yuzhu Chen, Jinqiu Qi, Yongqian Yang, Yao Lu, Zhiping Su, Yong Zhuo, De Wu   +13 more
wiley   +1 more source

Property Crime and Socioeconomic Factors

Open Journal of Social Sciences, 2017
This paper analyzes the relationship between property crime and socioeconomic factors by choosing section data of American states from 2011 to 2015. The research shows that: 1) The factors—unemployment rate, median household income and education level do not strong affect the change of property crime; the covered people of unemployment insurance policy
openaire   +3 more sources

Anti‐Swelling Hydrogel Combined With Nucleus Pulposus Cell Exosomes and Senolytic Drugs Efficiently Repair Intervertebral Disc Degeneration

Advanced Science, EarlyView.
In this study, a bifunctional anti‐swelling hydrogel system is developed, which encapsulated anti‐senescence drugs quercetin, dasatinib, nucleus pulposus‐derived exosomes (NP‐Exo) to clear senescent nucleus pulposus cells, regulate the inflammatory disc microenvironment, and enhance nucleus pulposus cells activity, ultimately promoting the repair of ...
Songfeng Chen, Hao Han, Yuhao Zhang, Longyu Li, Zhishuo Wang, Jiaming Zhang, Liang Han, Hongwei Kou, Guowei Shang, Chunfeng Shang, Zikuan Leng, Keya Mao, Chengwei Li, Lin Jin, Hongjian Liu   +14 more
wiley   +1 more source