Results 151 to 160 of about 1,427,305 (357)
Advanced Science, EarlyView.Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu +10 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Assessment of Extrapulmonary Tuberculosis in Two Provinces of Turkey
Iranian Journal of Public Health, 2016 Background: Tuberculosis (TB) is one of the main health issues in Turkey. Extrapulmonary TB cases have significant proportion comparing pulmonary TB cases.
Dursun TATAR +5 more
doaj
Economic Policies, Political Considerations and Overall Health [PDF]
Socioeconomic factors play a crucial role in determining physiological and psychological health levels of the population. The level of unemployment, income inequality and poverty levels are largely affected by economic policies and the economic cycles ...
Stavros A. Drakopoulos
core
Advanced Science, EarlyView.SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li +14 more
wiley +1 more source
Socioeconomic factors and injuries. [PDF]
Journal of Epidemiology and Community Health, 1995 S N, Forjuoh, S R, Dearwater
openaire +2 more sources
Advanced Science, EarlyView.A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng +10 more
wiley +1 more source
Analysis of Socioeconomic Factors that Dampen the Flow of Foreign Direct Investment
, 2015 Khawaja Asif Mehmood, Sallahuddin Hassan
openalex +2 more sources
(209) Association of socioeconomic factors with pain and function in older adults with knee osteoarthritis [PDF]
, 2016 T. Sampiero +16 more
openalex +1 more source
Advanced Science, EarlyView.A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie +8 more
wiley +1 more source