Results 181 to 190 of about 14,232,637 (407)

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

A systematic review and meta-regression on international trends in the incidence of ulcerative colitis in children and adolescents associated with socioeconomic and geographic factors [PDF]

, 2023
Jens Weidner, Ivana Kern, Ines Reinecke, Franziska Bathelt, Ulf Manuwald, Elisa Henke, Michéle Zoch, Ulrike Rothe, Joachim Kugler   +8 more
openalex   +1 more source

Integrated Self‐Powered Sensors for Continuous Foot Health Monitoring via Laser‐Induced MXene‐Composited Graphene Hybrids From Lignocellulose

Advanced Science, EarlyView.
This study presents a high‐performance foot‐monitoring platform based on lignocellulose‐derived laser‐induced MXenecomposited graphene hybrids (LIG@MXene). The LIG@MXene exhibits markedly improved electrical conductivity, structural stability, and multifunctionality, enabling integrated energy harvesting, sensing, Joule heating, and supercapacitor ...
Peilong Zhao, Xiaofei Mao, Jiashu Song, Man Liu, Luxue Cui, Mingyang Liu, Nan Zhao, Jingqing Gao, Yuguang Zhou   +8 more
wiley   +1 more source

Understanding and integrating socioeconomic factors into the design and management of marine protected areas [PDF]

, 2022
Georgina G. Gurney
openalex   +1 more source

Economic Policies, Political Considerations and Overall Health [PDF]

Socioeconomic factors play a crucial role in determining physiological and psychological health levels of the population. The level of unemployment, income inequality and poverty levels are largely affected by economic policies and the economic cycles ...
Stavros A. Drakopoulos
core  

The state of birth weight in the north of Iran [PDF]

, 2009
Introduction and object: This study was designed for determining the birth weight and some other factors affecting rural newborn children in the north of Iran (south east of Caspian sea).
Marjani, A., Rahmati, R., Veghari, G.
core  

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Socioeconomic factors and their relationship with nutritional status in children under 3 years of age in Jipijapa

, 2022
Mirella Dolores Cedeño, Adís Anicia Luna Báez, Aida Monserrate Macías Álvia, Estrella Marisol Mera Quijije   +3 more
openalex   +2 more sources

Parenting behaviours and children's development from infancy to early childhood: Changes, continuities, and contributions [Wider Benefits of Learning Research Report No. 22] [PDF]

, 2007
This study investigated how children and parenting behaviours change from infancy to early childhood, how parenting influences concurrent and future child development, and whether parenting itself is affected by and responsive to child development.
Feinstein, Leon, Gutman, Leslie
core