Results 41 to 50 of about 529,326 (314)

Invesigate how cultural and socioeconomic factors influence oral cancer prevention behaviors, screening uptake, and treatment outcomes

Journal of Pharmacy and Bioallied Sciences
Background: Oral cancer is a significant global health issue, with prevention and early detection being pivotal for improved outcomes. This study investigates the impact of cultural and socioeconomic factors on oral cancer prevention behaviors, screening
Madhu Ranjan, Tushar, Nirav Hemant Parekh, Arti Dixit, Pinaki Rakshit, Bhagyashree P Agre, Bhumika Kamal Badiyani, Amit Kumar   +7 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Socioeconomic factors and asthma control in children [PDF]

Pediatric Pulmonology, 2008
AbstractObjectivesThe objective of this study was to evaluate the association between socioeconomic factors and asthma control in children, as defined by the Canadian Pediatric Asthma Consensus Guidelines.Patients and MethodsCross‐sectional data from a completed study of 879 asthmatic children between the ages of 1 and 18 residing in the Greater ...
Richard H. Glazier, Richard H. Glazier, Richard H. Glazier, Wendy J. Ungar, Wendy J. Ungar, Shannon F. Cope   +5 more
openaire   +3 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Patient’s Comprehension of Prescriptions at Municipal Urban Health Centre, Mumbai [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Patient's often fail to follow the prescription given by the doctor. Patients understanding of the prescription play an important role in completion of treatment and quick recovery from the illness.
Amrita P Rao, Gajanan D Velhal, Deepak S Khismatrao   +2 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Association between socioeconomic status and the utilization of maternal health services in Nigeria

Iranian Journal of Nursing and Midwifery Research, 2023
Background: Maternal health is the mother's state of well-being before, during, and after conception. Studies have suggested that the increasing maternal mortality rate is preventable provided maternal health services are accessible during pregnancy ...
Bukola T Maitanmi, Abiodun A Adelaja, Damilola R Okunola, Julius O Maitanmi, Yetunde O Tola, Oluwadamilare Akingbade   +5 more
doaj   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Socioeconomic factors, psychological factors, and function in adults with chronic musculoskeletal pain from rural Nepal

Journal of Pain Research, 2018
Saurab Sharma,1,2 Anupa Pathak,1,3 Jyoti Jha,1,4 Mark P Jensen5 1Department of Physiotherapy, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal; 2Center for Musculoskeletal Outcomes Research, Department of Surgical Sciences, Dunedin ...
Sharma S, Pathak A, Jha J, Jensen MP
doaj