Results 161 to 170 of about 3,172,529 (291)

Two Family Gradients in Children's Physical Activity and Fitness: Socioeconomic Position, Family Structure, and Where They Diverge. [PDF]

Healthcare (Basel)
Zhang Y, Pan X, Gao Y, Hu H.
europepmc   +1 more source

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

Socioeconomic Position in Early Life and Childhood Cardiovascular Health Measures: An International Cross-Cohort Study. [PDF]

J Am Heart Assoc
Gamage K, Pätsi S, Chen T, Mooney K, Sebert S, Priest N, Mansell T, Burgner D, Barwon Infant Study Investigator Group.   +8 more
europepmc   +1 more source

Phase‐Programmed Microneedles Enable Sequential Hydrogen and Quercetin Release for Scar‐Reduced Regeneration of Burn Wounds

Advanced Science, EarlyView.
A phase‐programmed microneedle patch, comprising a poly (lactic‐co‐glycolic acid) (PLGA) shell and a sulfobutylether‐β‐cyclodextrin (SBECD) core, is designed for sequential hydrogen and quercetin release for scar‐reduced regeneration of burn wounds. ABSTRACT Burn wounds complicated by bacterial infection and fibrotic scarring remain a major clinical ...
Yongnian Zeng, Zhigang Chu, Huiyuan Yang, Wen Zhang, Peng Jiang, Jiapeng Lei, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Psychological distress in urban Iran: a multilevel analysis of socioeconomic position and context. [PDF]

BMC Psychol
Alipour F, Rafiey H, Salimi Y, Ahmadi S, Paykani T.   +4 more
europepmc   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source

Individual and Contextual Socioeconomic Position on Type 2 Diabetes Risk in LMICs: A Multilevel Analysis. [PDF]

Ann N Y Acad Sci
Fahimi R, Alrubayyi A, Hassan M, Barber TM, Uthman OA.   +4 more
europepmc   +1 more source

Microenvironment‐Responsive Biomimetic Hydrogels Delivering Cistanche Deserticola‐Derived Nanovesicles for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
An injectable, microenvironment‐responsive hydrogel (HAPOCS@CDNVs) is developed for sustained delivery of Cistanche deserticola‐derived nanovesicles (CDNVs). By scavenging ROS, restoring mitochondrial function, and attenuating SASP, this platform effectively suppresses nucleus pulposus cell senescence and facilitates extracellular matrix reconstruction,
Ning Xu, Xiaoyu Cai, Xiaofu Tang, Weidong Liang, Linsong Teng, Yudong Jing, Haifeng Hu, Yuhao Duan, Mingjie Kuang, Lei Zhang, Shijie Han, Weibin Sheng   +11 more
wiley   +1 more source

Life-course socioeconomic position and health in older adulthood: a causal mediation analysis in the 1958 British Birth Cohort. [PDF]

Lancet Reg Health Eur
Guo Y, Pelikh A, Ploubidis GB, Goodman A.   +3 more
europepmc   +1 more source

Targeting Kynurenine Synthesis Attenuated Cigarette Smoke‐Induced COPD‐Like Lung Injury Driven by TALDO1‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Cigarette smoke induces airway epithelial TALDO1 upregulation and L‐kynurenine accumulation, driving mitochondrial injury with elevated mtROS, reduced Δψm, ATP, and OCR. This links to lung inflammation, alveolar destruction, and lung function damage, all attenuated by Epacadostat or Taldo1 reduction.
Wenjing Wang, Mindan Wu, Yuanlan Yang, Zemin Chen, Jiawei Yan, Xuan Jin, Yachao Cui, Feng Zhang, Haiqing Li, Wensheng Chen, Yumin Zhou, Leqing Zhu, Wei Tu, Pixin Ran   +13 more
wiley   +1 more source