Results 51 to 60 of about 222,094 (300)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Influencia del estatus socioeconómico (SES) sobre la variabilidad antropométrica en estudiantes universitarios del País Vasco (España) / Influence of socioeconomic status in anthropometric variability in university students (Basque Country, Spain)

Revista Argentina de Antropología Biológica, 2016
Los estudios sobre el impacto del estatus socioeconómico (SES) en las dimensiones corporales tienen una amplia tradición científica, ya que la variabilidad y evolución de estas son un reflejo del bienestar poblacional.
Esther Rebato, María J. Muñoz-Cachón
doaj   +2 more sources

Longitudinal associations between socioeconomic status and cardiovascular disease in a Chinese population: Evidence from CHARLS.

PLoS ONE
ImportanceThe relationship between socioeconomic status and cardiovascular disease among the general Chinese population is inconclusive.ObjectiveThis study aims to investigate the relationship between socioeconomic status and cardiovascular disease in ...
Qingping Zeng, Mengqian Liao, Yu Li, Fei She, Ping Zhang   +4 more
doaj   +1 more source

Income and education predict elevated depressive symptoms in the general population: results from the Gutenberg health study

BMC Public Health, 2019
Background Socioeconomic status (SES) has a strong association with depression or physical and mental health in general. However, as SES is a multifaceted construct these associations are not easy to explain.
Jasmin Schlax, Claus Jünger, Manfred E. Beutel, Thomas Münzel, Norbert Pfeiffer, Philipp Wild, Maria Blettner, Jasmin Ghaemi Kerahrodi, Jörg Wiltink, Matthias Michal   +9 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Widening access in selection using situational judgement tests: evidence from the UKCAT [PDF]

, 2016
CONTEXT Widening access promotes student diversity and the appropriate representation of all demographic groups. This study aims to examine diversity-related benefits of the use of situational judgement tests (SJTs) in the UK Clinical Aptitude Test ...
Corstjens, Jan, Lievens, Filip, Martin, S, Nicholson, S, Patterson, F   +4 more
core   +2 more sources

Socioeconomic Status (SES) and Language Policy in the United States

, 2015
The primary argument of this issue brief is that socioeconomic status can have a significant effect on English language learning and access to appropriate English language policy in the United States. This will have a continued effect on how low SES non-Native speakers engage in conventional means of political participation in the U.S..
Li, Amy Lu, Smith, Raymond Arthur
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Is the educational health gap increasing for women? Results from Catalonia (Spain) [PDF]

, 2015
Health expectancies vary worldwide according to socioeconomic status (SES). The lower SES usually show health disadvantage and the higher SES a health advantage compared to the average.
Alcañiz, Manuela, Solé i Auró, Aïda
core