Results 1 to 10 of about 5,928 (100)

Regulation of Na+/H+ exchangers, Na+/K+ transporters, and lignin biosynthesis genes, along with lignin accumulation, sodium extrusion, and antioxidant defense, confers salt tolerance in alfalfa

Frontiers in Plant Science, 2022
Accumulation of high sodium (Na+) leads to disruption of metabolic processes and decline in plant growth and productivity. Therefore, this study was undertaken to clarify how Na+/H+ exchangers and Na+/K+ transporter genes contribute to Na+ homeostasis ...
Md Atikur Rahman, Jae Hoon Woo, Sang-Hoon Lee, Hyung Soo Park, Ahmad Humayan Kabir, Ahmad Humayan Kabir, Ali Raza, Ayman El Sabagh, Ayman El Sabagh, Ki-Won Lee   +9 more
doaj   +1 more source

Genome-Wide Identification and Expression Analysis of the NHX (Sodium/Hydrogen Antiporter) Gene Family in Cotton

Frontiers in Genetics, 2020
The sodium/hydrogen antiporter (NHX) gene family with the Na+/H+ exchange protein domain is a transporter of sodium and hydrogen ions and plays an important role in the response of plants to salt stress.
Xiaokang Fu, Zhengying Lu, Hengling Wei, Jingjing Zhang, Xu Yang, Aimin Wu, Liang Ma, Meng Kang, Jianhua Lu, Hantao Wang, Shuxun Yu   +10 more
doaj   +1 more source

Exogenous Potassium (K⁺) Positively Regulates Na⁺/H⁺ Antiport System, Carbohydrate Metabolism, and Ascorbate–Glutathione Cycle in H₂S-Dependent Manner in NaCl-Stressed Tomato Seedling Roots

Plants, 2021
Potassium (K+) is one of the vital macronutrients required by plants for proper growth and blossoming harvest. In addition, K+ also plays a decisive role in promoting tolerance to various stresses.
M. Nasir Khan, Soumya Mukherjee, Asma A. Al-Huqail, Riyadh A. Basahi, Hayssam M. Ali, Bander M. A. Al-Munqedhi, Manzer H. Siddiqui, Hazem M. Kalaji   +7 more
doaj   +1 more source

Proteomic profiling of sweat in patients with cystic fibrosis provides new insights into epidermal homoeostasis

Skin Health and Disease, 2023
Background A high proportion of patients with Cystic Fibrosis (CF) also present the rare skin disease aquagenic palmoplantar keratoderma. A possible link between this condition and absence of a functional CF Transmembrane conductance Regulator protein in
Matthieu Cornet, Thao Nguyen‐Khoa, Mairead Kelly‐Aubert, Vincent Jung, Frédérique Chedevergne, Muriel Le Bourgeois, Laura Aoust, Kévin Roger, Chiara Ida Guerrera, Isabelle Sermet‐Gaudelus   +9 more
doaj   +1 more source

[Pt(O,O'-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR Pathway. [PDF]

PLoS ONE, 2014
We previously showed that [Pt(O,O'-acac)(γ-acac)(DMS)] ([Pt(acac)2(DMS)]) exerted substantial cytotoxic effects in SH-SY5Y neuroblastoma cells, and decreased metalloproteases (MMPs) production and cells migration in MCF-7 breast cancer cells.
Antonella Muscella, Carla Vetrugno, Nadia Calabriso, Luca Giulio Cossa, Sandra Angelica De Pascali, Francesco Paolo Fanizzi, Santo Marsigliante   +6 more
doaj   +1 more source

Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea

Frontiers in Microbiology, 2017
Mrp (Multiple resistance and pH) antiporter was identified as a gene complementing an alkaline-sensitive mutant strain of alkaliphilic Bacillus halodurans C-125 in 1990.
Masahiro Ito, Masahiro Ito, Masato Morino, Masato Morino, Terry A. Krulwich   +4 more
doaj   +1 more source

Whole-genome identification and expression analysis of K+ efflux antiporter (KEA) and Na+/H+ antiporter (NHX) families under abiotic stress in soybean

Journal of Integrative Agriculture, 2015
Sodium toxicity and potassium insufficient are important factors affecting the growth and development of soybean in saline soil. As the capacity of plants to maintain a high cytosolic, K+/Na+ ratio is the key determinant of tolerance under salt stress ...
Hua-tao CHEN, Xin CHEN, Bing-yue WU, Xing-xing YUAN, Hong-mei ZHANG, Xiao-yan CUI, Xiao-qing LIU   +6 more
doaj   +1 more source

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet, Christ, Michael, Eisen, Christoph, Theisen, Karl, Wehling, Martin   +4 more
core   +1 more source

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake.

PLoS ONE, 2020
Disruption of blood-brain barrier integrity and dramatic failure of brain ion homeostasis including fluctuations of pH occurs during cortical spreading depression (CSD) events associated with several neurological disorders, including migraine with aura ...
Erika Liktor-Busa, Kiera T Blawn, Kathryn L Kellohen, Beth M Wiese, Vani Verkhovsky, Jared Wahl, Anjali Vivek, Seph M Palomino, Thomas P Davis, Todd W Vanderah, Tally M Largent-Milnes   +10 more
doaj   +1 more source

MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AS SIGNALLING MOLECULES OF INTRACELLULAR PATHWAYS TRIGGERED BY THE CARDIAC RENIN-ANGIOTENSIN II-ALDOSTERONE SYSTEM (RAAS).

Frontiers in Physiology, 2013
Mitochondria represent major sources of basal reactive oxygen species (ROS) production of the cardiomyocyte. The role of ROS as signalling molecules that mediate different intracellular pathways has gained increasing interest among physiologists in the ...
Verónica Celeste De Giusti, Claudia Irma Caldiz, Irene Lucía Ennis, Néstor Gustavo Pérez, Horacio Eugenio Cingolani, Ernesto Alejandro Aiello   +5 more
doaj   +1 more source