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Sodium-Glucose Co-Transport Inhibitors
Drugs, 2010The kidney plays a major role in glucose homeostasis because of its role in gluconeogenesis and the glomerular filtration and reabsorption of glucose in the proximal convoluted tubules. Approximately 180 g of glucose is filtered daily in the glomeruli of a normal healthy adult. Typically, all of this glucose is reabsorbed with
Joshua J, Neumiller +2 more
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[Sodium-glucose co-transporter 2 inhibitor for diabetes?].
Nederlands tijdschrift voor geneeskunde, 2016Following initial expectations, raised by the results of the United Kingdom Prospective Diabetes Study, intervention studies aimed at tight glucose control did not reduce cardiovascular disease. The EMPA-REG OUTCOME, an empagliflozin intervention study in over 7,000 patients with type 2 diabetes mellitus and a history of cardiovascular disease, for the
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Comment on Sodium-Glucose Co-Transporter 2 Inhibitors and Heart Failure
The American Journal of Cardiology, 2020Erkan Cure, Medine Cumhur Cure
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A kidney perspective on the mechanism of action of sodium glucose co-transporter 2 inhibitors
Cell Metabolism, 2021Taha Sen, Hiddo J L Heerspink
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