Results 271 to 280 of about 118,941 (325)

Update on the Efficacy and Safety of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Chronic Diseases: A Systematic Review and Meta-Analysis. [PDF]

Medicina (Kaunas)
Liang IC, Chang HH, Lai YJ, Chan CM, Sung CH, Pu CM, Chang DC, Ho CC, Hung CF.   +8 more
europepmc   +1 more source

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

Animal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng, GuoYan Wang, YuanYuan Zhu, YiNing Zheng, JunHu Yao, Lei Chen, Lu Deng   +6 more
wiley   +1 more source

Real-world effectiveness and safety of sodium-glucose co-transporter 2 inhibitors in chronic kidney disease. [PDF]

Sci Rep
Hunsuwan S, Boongird S, Ingsathit A, Ponthongmak W, Unwanatham N, McKay GJ, Attia J, Thakkinstian A.   +7 more
europepmc   +1 more source

Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition

Arthritis &Rheumatology, EarlyView.
Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H. W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Sodium glucose co-transporter 2 inhibitors safety depending on their adverse drug reactions and glucose monitoring parameters in type 2 diabetes mellitus.

Indian J Pharmacol
Bellapu D, Darwin R.
europepmc   +1 more source

Effects of Sodium-Glucose Co-Transporter 2 Inhibitors on Serum Chloride Concentrations in Patients with Heart Failure. [PDF]

J Cardiovasc Dev Dis
Jurin I, Ivanović Mihajlović V, Šakić Z, Pavlov M, Šipić T, Vitlov P, Falak H, Grizelj D, Manola Š, Udovičić M.   +9 more
europepmc   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

The impact of sodium-glucose co-transporter-2 inhibitors on serum sodium and potassium in patients with Heart Failure: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Amani-Beni R, Darouei B, Shafie D, Mortaheb M, Malakoutikhah M, Ebrahimi A, Heidari-Hasanabadi S, Rabiee Rad M, Ghasempour Dabaghi G, Mazaheri-Tehrani S, Amini-Salehi E, Abhari AP, Heidarpour M.   +12 more
europepmc   +1 more source

Adaptive and Biochemical Responses of Dictyosphaerium sp. AM‐2024a to Environmental Conditions and Microplastic Interactions: Synergy of Biofuel Production With Pollution Mitigation

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This study investigates the physiological and biochemical responses of a newly isolated microalgal strain, Dictyosphaerium sp. AM‐2024a, identified through 18S rDNA sequencing, under varying environmental conditions and microplastic (MP) interactions.
Khushboo Iqbal, Arti Mishra, Smitha Mony Sreedharan   +2 more
wiley   +1 more source

Resistance Patterns of Urinary Tract Pathogens Isolated from Patients with Type 2 Diabetes Mellitus on Sodium Glucose Co-transporter 2 Inhibitors Admitted in a Tertiary Hospital in the Philippines: A Single-Center Retrospective Cohort Study. [PDF]

J ASEAN Fed Endocr Soc
Rudinas CR, Tan CC.
europepmc   +1 more source