Results 31 to 40 of about 35,545 (253)

Eligibility of outpatients with chronic heart failure for sodium–glucose co‐transporter‐2 inhibitors

open access: yesESC Heart Failure, 2021
Aims Sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) have been shown to have a relevant role in the prevention of hospitalizations for heart failure and improvement in the life expectancy of patients with diabetes and outpatients with chronic heart ...
Gianmarco Angelini   +11 more
doaj   +1 more source

Biomolecular Mechanisms of Cardiorenal Protection with Sodium-Glucose Co-Transporter 2 Inhibitors

open access: yesBiomolecules, 2022
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia and associated with an increased risk of morbidity and mortality, primarily from cardiovascular and renal diseases. Sodium-glucose cotransporter 2 inhibitors (SGLT2-Is)
Francesca Romana Prandi   +8 more
doaj   +1 more source

Sodium-glucose co-transporter 2 (SGLT2) inhibitors: a growing class of anti-diabetic agents

open access: yesDrugs in Context, 2014
Although several treatment options are available to reduce hyperglycemia, only about half of individuals with diagnosed diabetes mellitus (DM) achieve recommended glycemic targets.
Eva M Vivian
doaj   +1 more source

Sodium-glucose co-transporter-2 inhibitors in heart failure and chronic kidney disease: the role of empagliflozin

open access: yesРоссийский кардиологический журнал, 2021
The development of chronic kidney disease (CKD) is a risk factor not only for cardiovascular diseases, but also for heart failure (HF). This article is a literary review on the use of Sodium-glucose co-transporter-2 (NGLT2) inhibitors in patients with ...
M. M. Batyushin
doaj   +1 more source

Sodium-Glucose Co-transporter 2 Inhibitors in the Failing Heart: a Growing Potential [PDF]

open access: yesCardiovascular Drugs and Therapy, 2020
AbstractSodium-glucose co-transporter 2 inhibitors (SGLT2i) are a new drug class designed to treat patients with type 2 diabetes (T2D). However, cardiovascular outcome trials showed that SGLT2i also offer protection against heart failure (HF)–related events and cardiovascular mortality.
Brito, Dulce   +9 more
openaire   +3 more sources

Sodium glucose co-transporter 2 inhibitors in patients with resistant hypertension: a case study

open access: yesJRSM Open, 2016
Sodium glucose co-transporter 2 inhibitors lower blood pressure by osmotic diuresis and can be considered in diabetic patients with resistant hypertension.
Amira Obeid   +3 more
doaj   +1 more source

Efficacy of sodium-glucose co-transporter-2 inhibitors in patients with heart failure

open access: yesРоссийский кардиологический журнал, 2021
The article analyzes the new results of randomized clinical trials on the use of sodium-glucose co-transporter-2 inhibitors in patients with cardiovascular diseases, heart failure with and without type 2 diabetes.
E. V. Kovalenko   +3 more
doaj   +1 more source

The Efficacy and Safety of the Combination Therapy With GLP-1 Receptor Agonists and SGLT-2 Inhibitors in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis

open access: yesFrontiers in Pharmacology, 2022
Aims: Glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors play a key role in the treatment of type 2 diabetes mellitus.
Chen Li   +7 more
doaj   +1 more source

Sodium–glucose co-transporter 2 inhibitors for the treatment of cardio-renal syndrome

open access: yesEuropean Heart Journal Supplements, 2022
Abstract The 2021 guidelines of the European Society of Cardiology on the diagnosis and therapy of heart failure (HF) introduced relevant changes in the pharmacological treatment of chronic HF. Among these, certainly the most significant was the introduction in the therapeutic flow-chart (with the highest recommendation level) of the ...
Cice, Gennaro   +2 more
openaire   +2 more sources

Impact of SGLT2 inhibitors treatment on the chronic kidney disease in people with type 2 diabetes

open access: yesJournal of Education, Health and Sport, 2022
Diabetes is the most common cause of CKD (chronic kidney disease). CKD is also one of the most important diabetic complication. SGLT2 (sodium glucose co‐transporter‐2) inhibitors are new class of medication used to lower high blood glucose level in ...
Marcin Czarkowski   +3 more
doaj   +1 more source

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