Results 1 to 10 of about 186,093 (261)

Genito-urinary infection risk estimates during sodium glucose co-transporter 2 inhibitor exposure in everyday clinical practice. [PDF]

open access: yesFarmacja Polska, 2021
Genito-urinary infection risk estimates during sodium glucose co-transporter 2 inhibitor exposure in everyday clinical practice. Type 2 diabetes mellitus, cardiovascular diseases and congestive heart failure are known to be a cause of growing ...
Beata Jacuś   +3 more
doaj   +1 more source

The Efficacy and Safety of the Combination Therapy With GLP-1 Receptor Agonists and SGLT-2 Inhibitors in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis

open access: yesFrontiers in Pharmacology, 2022
Aims: Glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors play a key role in the treatment of type 2 diabetes mellitus.
Chen Li   +7 more
doaj   +1 more source

Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
Background Although cardiovascular outcome trials using sodium-glucose cotransporter-2 inhibitors (SGLT-2i) showed a reduction in risk of 3-point major adverse cardiovascular events (MACE), they did not demonstrate beneficial effects on stroke risk ...
Seung Eun Lee   +5 more
doaj   +1 more source

Anti-Arrhythmic Effects of Sodium-Glucose Co-Transporter 2 Inhibitors

open access: yesFrontiers in Pharmacology, 2022
Arrhythmias are clinically prevalent with a high mortality rate. They impose a huge economic burden, thereby substantially affecting the quality of life.
Yuling Jing   +3 more
doaj   +1 more source

Sodium-dependent glucose transporter 1 and glucose transporter 2 mediate intestinal transport of quercetrin in Caco-2 cells

open access: yesFood & Nutrition Research, 2020
Background: The role of glucose transporters in the transport of flavonoids remains ambiguous. Objective: In this study, we examined whether quercitrin would be absorbed intactly in modeled Caco-2 cells, as well as determined the involvement of sodium ...
Suyun Li   +6 more
doaj   +1 more source

Sodium-glucose co-transporter 2 inhibitors – a review article

open access: yesJournal of Education, Health and Sport, 2019
Antihyperglycemic interventions have centered on increasing insulin availability, improving insulin sensitivity or restoring β-cell activity to normalize plasma glucose levels in patients with type 2 diabetes mellitus.
Marcin Makuch   +3 more
doaj   +3 more sources

Expression profiling of ascorbic acid–related transporters in human and mouse eyes [PDF]

open access: yes, 2016
PURPOSE: Ascorbic acid (AsA) is an important antioxidant in the eye. Ascorbic acid is usually transported by sodium-dependent AsA transporters (SVCTs), and dehydroascorbic acid (DHA) by glucose transporters (GLUTs).
Beebe, David   +10 more
core   +2 more sources

Sodium glucose transporter 2 (SGLT2) inhibition and ketogenesis

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Sodium glucose transporter 2 (SGLT2) inhibitors are a recently developed class of drug that have been approved for use in type 2 diabetes. Their unique extra-pancreatic glucuretic mode of action has encouraged their usage in type 1 diabetes as well.
Sanjay Kalra   +2 more
doaj   +1 more source

Glycemic Efficacy and Metabolic Consequences of an Empagliflozin Add-on versus Conventional Dose-Increasing Strategy in Patients with Type 2 Diabetes Inadequately Controlled by Metformin and Sulfonylurea [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background We assessed the glucose-lowering efficacy of adding empagliflozin versus dose escalating existing medications in patients with uncontrolled type 2 diabetes (T2D).
Yujin Shin   +4 more
doaj   +1 more source

Effects of canagliflozin on cardiovascular biomarkers in older adults with type 2 diabetes [PDF]

open access: yes, 2017
Background: Sodium glucose co-transporter 2 (SGLT2) inhibitors may reduce cardiovascular and heart failure risk in patients with type 2 diabetes mellitus (T2DM).
Butler, Javed   +6 more
core   +1 more source

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