Advanced Functional Materials, EarlyView.A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui +10 more
wiley +1 more source
Exploring plant tolerance to biotic and abiotic stresses [PDF]
, 2007 Plants are exposed to many stress factors, such as drought, high salinity or pathogens, which reduce the yield of the cultivated plants or affect the quality of the harvested products. Arabidopsis thaliana was used as a model plant to study the responses
Karim, Sazzad
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The SGLT2 inhibitor empagliflozin for the treatment of type 2 diabetes mellitus: A bench to bedside review [PDF]
, 2014 INTRODUCTION: The treatment of type 2 diabetes mellitus (T2DM) continues to pose challenges for clinicians and patients. The dramatic rise in T2DM prevalence, which has paralleled the rise in obesity, has strained the healthcare system and prompted the ...
McGill, Janet B
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Frontier Advances of Emerging High‐Entropy Anodes in Alkali Metal‐Ion Batteries
Advanced Functional Materials, EarlyView.Recent advances in microscopic morphology control of high‐entropy anode materials for alkali metal‐ion batteries. Abstract With the growing demand for sustainable energy, portable energy storage systems have become increasingly critical. Among them, the development of rechargeable batteries is primarily driven by breakthroughs in electrode materials ...
Liang Du +14 more
wiley +1 more source
Advances in sodium-glucose transporter protein 2 inhibitors and tumors
Frontiers in OncologyTumor is a major challenge to global health and has received extensive attention worldwide due to its high degree of malignancy and poor prognosis. Although the clinical application of targeted therapy and immunotherapy has improved the status quo of ...
Jiaqi Wang, Wenyong Yang
doaj +1 more source
Sodium-glucose transporter-2 (SGLT2; SLC5A2) enhances cellular uptake of aminoglycosides.
PLoS ONE, 2014 Aminoglycoside antibiotics, like gentamicin, continue to be clinically essential worldwide to treat life-threatening bacterial infections. Yet, the ototoxic and nephrotoxic side-effects of these drugs remain serious complications.
Meiyan Jiang +5 more
doaj +1 more source
A model‐based meta analysis study of sodium glucose co‐transporter‐2 inhibitors
CPT: Pharmacometrics & Systems Pharmacology, 2023 Type 2 diabetes mellitus (T2DM) agent sodium‐glucose co‐transporter 2 (SGLT2) inhibitors show special benefits in reducing body weight and heart failure risks.
Xueting Yao +5 more
doaj +1 more source
[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice [PDF]
, 2017 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give ...
Akhter, Farjana +9 more
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Advanced Functional Materials, EarlyView.This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang +12 more
wiley +1 more source
Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]
, 2019 Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria +4 more
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