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A safety update on sodium glucose co‐transporter 2 inhibitors

Diabetes, Obesity and Metabolism, 2019
Sodium glucose co‐transporter 2 inhibitors (SGLT2is) are the first class of glucose lowering agent to be shown to reduce cardiovascular events. They are generally well tolerated with infrequent serious adverse events. The most frequent side effect is genital mycotic infections with candida species that are usually mild to moderate in severity, easily ...
openaire   +2 more sources

Emerging sodium/glucose co-transporter 2 inhibitors for type 2 diabetes

Expert Opinion on Emerging Drugs, 2013
Type 2 diabetes mellitus (T2DM) is a public health challenge globally. Numerous treatments are available which can improve insulin sensitivity or stimulate its secretion including biguanides, sulphonylureas and glitazones, as well as insulin, GLP-1 agonists and DPP-IV inhibitors.
Luke D, Boyle, John P H, Wilding
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Caffeine intake enhances the benefits of sodium glucose transporter 2 inhibitor

Diabetes/Metabolism Research and Reviews, 2016
AbstractBackgroundThe effect of sodium glucose transporter 2 (SGLT‐2) inhibitors is dependent on the glomerular filtration rate. It has been reported that caffeine intake increases glomerular filtration rate. However, the effect of caffeine intake on urinary glucose excretion in patients who take SGLT‐2 inhibitors is unclear.MethodsSix patients with ...
Yoshitaka Hashimoto   +8 more
openaire   +2 more sources

Effect of sodium-glucose co-transporter 2 inhibitors on hepatic parameters: A systematic review and meta-analysis of randomized controlled trials

Pharmacological Research, 2021
Luis E Simental-Mendía   +2 more
exaly  

Potential drug-drug interaction between sodium-glucose co-transporter 2 inhibitors and statins: pharmacological and clinical evidence

Expert Opinion on Drug Metabolism and Toxicology, 2021
Christos Kontogiorgis   +2 more
exaly  

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