Results 211 to 220 of about 357,651 (286)

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Citric Acid and Sodium Bicarbonate as an Alternative Carbon Dioxide Source for Mosquito Surveillance. [PDF]

Insects
Hong C, Brookes VJ, Zadoks RN, Webb CE.
europepmc   +1 more source

The Primary Moral Problem in Pernicious Vomiting in Pregnancy [PDF]

, 1938
Latchford, J. K.
core   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Clinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol   +4 more
wiley   +1 more source

Enhancing Chemical Stability and Bioavailability of Aneratrigine Capsules via Dry Granulation: Addressing Stability Challenges in Sodium Bicarbonate-Containing Formulations for Clinical Development. [PDF]

Pharmaceutics
Cha KI, Kim GE, Seol JH, Kim DW, Lee S.
europepmc   +1 more source

A Simple Regeneration Process Using a CO2‐Switchable‐Polarity Solvent for Cellulose Hydrogels

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The effect of transformation of the anion chemical structure on cellulose solubility by flowing CO2 gas into aqueous pyrrolidinium hydroxide solutions was investigated. The changes in anion structure allowed for the modulation of cellulose solubility in aqueous pyrrolidinium hydroxide solutions, thus establishing a simple and safe cellulose ...
Arata Matsui, Deandra Ayu Putri, Morgan L. Thomas, Yuko Takeoka, Masahiro Rikukawa, Masahiro Yoshizawa‐Fujita   +5 more
wiley   +1 more source

Protocol summary and statistical analysis plan for the sodium bicarbonate for metabolic acidosis in the intensive care unit (SODa-BIC) trial. [PDF]

Crit Care Resusc
Serpa Neto A, McNamara M, Cooper J, Fujii T, Higgins A, Hodgson C, Navarra L, Nichol A, Peake S, Rea-Neto A, Secombe P, See E, Taylor P, Young M, Zampieri FG, Young P, Bellomo R, Udy A, SODa-BIC investigators.   +18 more
europepmc   +1 more source

Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin

Drug Testing and Analysis, EarlyView.
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand, Oliver Zierau, Detlef Thieme, Annekathrin Martina Keiler   +3 more
wiley   +1 more source

Effect of Oral and Topical Sodium Bicarbonate on Functional Recovery and Soccer-Specific Performance After Exercise-Induced Muscle Damage: A Randomized, Double-Blind, Placebo-Controlled Study. [PDF]

Nutrients
Gurton WH, Gough LA, Lynn A, Ranchordas MK.   +3 more
europepmc   +1 more source