Results 251 to 260 of about 366,375 (330)

Scalable production and biophysical characterization of an enzyme cocktail derived from human red blood cells

Biotechnology Progress, EarlyView.
Abstract Red blood cells (RBCs) play a critical role in oxygen and carbon dioxide transport, which is facilitated by RBC‐encapsulated hemoglobin (Hb) and carbonic anhydrase (CA). In addition, RBCs are constantly exposed to oxidative stress due to the intracellular reactive oxygen species (ROS) generated during Hb auto‐oxidation.
Mohd Asim Khan, Griffin J. Beyer, Naomi Goosby, Lilly Ortiz, Andre F. Palmer   +4 more
wiley   +1 more source

Efficacy and Safety of Nebulized Sodium Bicarbonate in Adults with COVID-19 (SODIC): A Randomized, Single-Center, Double-Blinded, Controlled Trial. [PDF]

Curr Ther Res Clin Exp
El-Badrawy MK, Elmorsey RA, Elhosiny MM, Shehta M, El-Hadidy TA, Abdelwahab IE, El-Badrawy A, Shokeir AA.   +7 more
europepmc   +1 more source

Effect of sodium bicarbonate, Neem and Yeast on different ruminal fluid parameters in sub-acute ruminal acidosis [PDF]

, 2019
Avinash B Thorat, Sudhirkumar T Borikar, Mfmf Siddiqui, Sudhir Rajurkar, S.D. Moregaonkar, Prabhakar B. Ghorpade   +5 more
openalex  

Scale‐up of a monoclonal antibody CHO fed‐batch production in stirred tank bioreactors: Effect of hydrodynamic conditions and feeding regimen

Biotechnology Progress, EarlyView.
Abstract Key hydrodynamic‐related parameters such as volumetric power input (P/V), impeller configuration, aeration strategy, and maximum gas sparge rate, as well as an appropriate feeding strategy, must be carefully selected to improve production yields in bioreactor.
Lucas Lemire, Sebastian‐Juan Reyes, Yves Durocher, Robert Voyer, Olivier Henry, Phuong Lan Pham   +5 more
wiley   +1 more source

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

Biotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert, Dylan G. Chitwood, Danqia Peng, Erin Redman, Ji Young L. Anderson, Nicholas R. Sandoval, Sarah W. Harcum   +6 more
wiley   +1 more source

Dimethyl Sulfate as Methylation Agent and Solvent in Highly Regioselective Synthesis of Methyl Salicylate Using Sodium Bicarbonate as a Base. [PDF]

ACS Omega
de Souza Freitas M, Nelson DL, de Sousa JVG, Wentz AP, Tada DB, Queiroz RC, Hurtado CR, de Macedo EF, Conceição K, Hurtado GR, Pessoa FLP, S Rodrigues YV, Bueno GP, Clososki GC, Barbosa SL.   +14 more
europepmc   +1 more source

Effect of dietary supplements of sodium bicarbonate on tissue calcium (Ca) and magnesium (Mg) levels in beef cattle. [PDF]

, 2010
Vladimir Kurčubić, Zoran Ilić, Marija Vukašinović, Radojica Đoković   +3 more
openalex  

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

Biotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu, Derek Silva, Melissa Holstein, Angela Lewandowski, Kristina Cunningham, Adam Sokolnicki, Bala Raghunath   +6 more
wiley   +1 more source

Electrocatalytic CO2 Reduction Coupled to Formate Fermentation: An Electro‐Bio Cascade Approach in Biocompatible Electrolytes

Chemistry – A European Journal, EarlyView.
CO2 utilization in industrial biotechnology: Rational design of a process cascade for electrochemical CO2 reduction linked with formate fermentation, supporting robust cell growth and high biomass yields. ABSTRACT Integration of electrochemical CO2 reduction with microbial fermentation enables conversion of CO2 into valuable chemicals but poses ...
Luciana Vieira, Jonathan Thomas Fabarius, Gabriela Rizzo Piton, Barbara Bohlen, Dhananjai Pangotra, Melanie Speck, Carina Sagstetter, Volker Sieber, Arne Roth   +8 more
wiley   +1 more source